Findings

What do systematic reviews say?

145 questions · 148 findings · 8 reviews

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No studies found 26 · 17.6%GRADE not reported 74 · 50%Very low 17 · 11.5%Low 24 · 16.2%Moderate 7 · 4.7%High 0 · 0%

Tempophore vs Mineral trioxide aggregate (MTA)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Tempophore showed no clear difference in radiological failure compared with mineral trioxide aggregate (MTA); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 2.69 [0.57, 12.70]
1 study · 56 participants
GRADE not reported

ProRoot MTA vs OrthoMTA

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

ProRoot MTA showed no clear difference in radiological failure compared with orthoMTA; GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 0.50 [0.05, 5.33]
1 study · 94 participants
GRADE not reported

Portland cement (PC) vs EMD (enamel matrix derivative) alone

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Portland cement (PC) showed no clear difference in radiological failure compared with enamel matrix derivative (EMD); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
24 months
RR 0.57 [0.18, 1.78]
1 study · 70 participants
GRADE not reported

Biodentine vs Calcium hydroxide (CH)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
6 and 12 months
No radiological failure in any participant; not estimable
1 study · 62 participants
GRADE not reported

Mineral trioxide aggregate (MTA) vs Full strength or 1:5 diluted formocresol (FC)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Mineral trioxide aggregate (MTA) probably leads to lower radiological failure compared with full strength or 1:5 diluted formocresol (FC) (moderate certainty).

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 0.41 [0.19, 0.89]
12 studies · 740 participants
Moderate

Self-etch adhesive + acetone-based total-etch adhesive vs Non-rinse conditioner + acetone-based total-etch adhesive

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether self-etch adhesive + acetone-based total-etch adhesive changes radiological failure compared with non-rinse conditioner + acetone-based total-etch adhesive (very low certainty).

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 and 24 months
RR 1.00 [0.07, 14.90]
1 study · 40 participants
Very low

Mineral trioxide aggregate (MTA) vs Portland cement (PC)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Mineral trioxide aggregate (MTA) showed no clear difference in radiological failure compared with portland cement (PC); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
24 months
RR 0.50 [0.10, 2.56]
3 studies · 130 participants
GRADE not reported

Bee propolis (one 500 mg capsule per day) vs Mineral trioxide aggregate (MTA)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Propolis showed no clear difference in radiological failure compared with mineral trioxide aggregate (MTA); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
6 months
RR 3.50 [0.80, 15.23]
1 study · 50 participants
GRADE not reported

Biodentine vs Formocresol (FC)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
6 months
No radiological failure in any participant; not estimable
1 study · 112 participants
GRADE not reported

Non-rinse conditioner + acetone-based total-etch adhesive vs Calcium hydroxide (CH)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether non-rinse conditioner + acetone-based total-etch adhesive changes radiological failure compared with calcium hydroxide (CH) (very low certainty).

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 and 24 months
RR 3.00 [0.13, 69.52]
1 study · 40 participants
Very low

Total-etching 36% phosphoric acid + acetone-based total-etch adhesive vs Calcium hydroxide (CH)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether total-etching 36% phosphoric acid + acetone-based total-etch adhesive changes radiological failure compared with calcium hydroxide (CH) (very low certainty).

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
24 months
RR 7.00 [0.38, 127.33]
1 study · 40 participants
Very low

Sodium hypochlorite (NaOCl) vs Ferric sulphate (FS)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Sodium hypochlorite (NaOCl) showed no clear difference in radiological failure compared with ferric sulphate (FS) (low certainty).

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 0.42 [0.17, 1.02]
2 studies · 110 participants
Low

Low-level laser therapy (LLLT) + calcium hydroxide vs Calcium hydroxide (CH)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Low-level laser therapy (LLLT) + calcium hydroxide showed no clear difference in radiological failure compared with calcium hydroxide (CH); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 0.50 [0.15, 1.64]
1 study · 30 participants
GRADE not reported

Low‐level laser therapy vs Low-level laser therapy (LLLT) + calcium hydroxide

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Low-level laser therapy (LLLT) showed no clear difference in radiological failure compared with low-level laser therapy (LLLT) + calcium hydroxide; GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 1.00 [0.24, 4.18]
1 study · 30 participants
GRADE not reported

Diode laser + mineral trioxide aggregate (MTA) vs Formocresol (FC) + zinc oxide and eugenol (ZOE)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Diode laser + mineral trioxide aggregate (MTA) showed no clear difference in radiological failure compared with formocresol (FC) + zinc oxide and eugenol (ZOE); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
mean 15.7 months
RR 4.00 [0.48, 33.42]
1 study · 52 participants
GRADE not reported

Calcium hydroxide (CH) vs Portland cement (PC)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Calcium hydroxide (CH) led to higher radiological failure compared with portland cement (PC); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 17.00 [1.07, 270.41]
1 study · 30 participants
GRADE not reported

Biodentine vs Propolis

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Biodentine showed no clear difference in radiological failure compared with propolis; GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
6 months
RR 0.43 [0.12, 1.47]
1 study · 50 participants
GRADE not reported

Vitapex (calcium hydroxide/iodoform) vs 3Mix (ciprofloxacin + metronidazole + minocycline)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Vitapex (calcium hydroxide/iodoform) showed no clear difference in radiological failure compared with 3Mix (ciprofloxacin + metronidazole + minocycline); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 1.83 [0.80, 4.19]
1 study · 50 participants
GRADE not reported

OrthoMTA vs RetroMTA

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

OrthoMTA showed no clear difference in radiological failure compared with retroMTA; GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 0.70 [0.12, 3.98]
1 study · 96 participants
GRADE not reported

Portland cement (PC) vs Portland cement + iodoform or Portland cement + zirconium oxide

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
up to 24 months
No events in any participant; not estimable
1 study · 30 participants
GRADE not reported