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What do systematic reviews say?

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Evidence found and GRADE certainty

70 questions · 70 findings · 2 reviews · Schizophrenia

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No studies found 33 · 47.1%GRADE not reported 2 · 2.9%Very low 19 · 27.1%Low 14 · 20%Moderate 2 · 2.9%High 0 · 0%

Non‐integrated models of care ‐ Assertive community treatment only/Intensive case management/Specialised case management services vs usual care

Lost to treatment · people with both severe mental illness and substance misuse

It is very uncertain whether non‐integrated models of care ‐ Assertive community treatment… changes leaving the study early: Lost to treatment compared with standard care (very low certainty).

1 finding from 1 review

Non‐integrated models of care ‐ Assertive community treatment only/Intensive case management/Specialised case management services vs usual care

Adverse event: Death ‐ not measured · people with both severe mental illness and substance misuse

The review found no eligible studies for this question.

1 finding from 1 review