Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

317 questions · 322 findings · 62 reviews · Eyes and Vision

No studies found 94 · 29.2%GRADE not reported 15 · 4.7%Very low 63 · 19.6%Low 91 · 28.3%Moderate 45 · 14%High 14 · 4.3%

PACK‐CXL with standard therapy vs Standard therapy alone (radiotherapy or chemoradiotherapy)

Proportion of participants with reduction in intraocular inflammation at 4 to 8 weeks Assessed by corneal keratic precipitates, anterior chamber cellular reaction, or other appropriate measure · participants of any age with confirmed cases of bacterial keratitis
1 finding from 1 review

Conventional occlusion vs atropine penalization

Quality of life (different measures and time points reported in the included studies) Assessed at different time points (17 weeks or 6 months) by patient preference or the Amblyopia Treatment Index questionnaire. · Participants of any age with either unilateral strabismic, anisometropic, or mixed (strabismic‐refractive) amblyopia; deprivation…
1 finding from 1 review

Vitrectomy vs scleral buckling

Adverse effects (cataract development, choroidal detachment, new/iatrogenic breaks, postoperative proliferative vitreoretinopathy, postoperative increase in intraocular pressure, development of cystoid macular oedema, macular pucker, strabismus) a... · people with simple rhegmatogenous retinal detachments

Pars plana vitrectomy (PPV) may leads to higher adverse effects (cataract development, choroidal detachment,… compared with scleral buckling (low certainty).

1 finding from 1 review

Summary of findings: intravitreal bevacizumab plus intravitreal steroid vs macular laser

Raised Intraocular Pressure at · adults with centre‐involving diabetic macular oedema

It is very uncertain whether summary of findings: intravitreal bevacizumab plus intravitreal… changes raised Intraocular Pressure at compared with macular laser (very low certainty).

1 finding from 1 review

Summary of findings: intravitreal bevacizumab plus intravitreal steroid vs intravitreal steroid

Raised Intraocular Pressure at · adults with centre‐involving diabetic macular oedema

It is very uncertain whether summary of findings: intravitreal bevacizumab plus intravitreal… changes raised intraocular pressure at 1 year at compared with intravitreal steroid (very low certainty).

1 finding from 1 review

Summary of findings: intravitreal bevacizumab plus intravitreal steroid vs intravitreal anti‐VEGF

Raised Intraocular Pressure at · adults with centre‐involving diabetic macular oedema

Summary of findings: intravitreal anti‐VEGF plus intravitreal steroid probably leads to higher raised intraocular pressure at compared with intravitreal anti‐VEGF (moderate certainty).

1 finding from 1 review

Surgery fee waiver with/without transport provision or reimbursement to improve access to cataract surgical services vs usual care

Change in the prevalence of cataract blindness · people with vision impairment caused by cataract

The review found no eligible studies for this question.

1 finding from 1 review