Any postoperative complication except bleeding (e.g. wound infection) · People on continuous VKA treatment undergoing minor oral surgery or dental extractions (eligibility included DOACs and all ages; all four…
Antifibrinolytic therapy - locally-applied tranexamic acid (TXA)… showed no clear difference in any postoperative complication except bleeding (e.g. wound infection) compared with placebo (placebo solution/mouthwash); GRADE not reported.
1 finding from 1 review
Number of participants with postoperative bleedings requiring intervention · People on continuous VKA treatment undergoing minor oral surgery or dental extractions (eligibility included DOACs and all ages; all four…
Antifibrinolytic therapy - locally-applied tranexamic acid (TXA)… probably leads to lower number of participants with postoperative bleedings requiring… compared with placebo (placebo solution/mouthwash) (moderate certainty).
1 finding from 1 review
Costs: direct cost of treatment · People of any age and either gender with post-extraction bleeding, regardless of type of teeth (anterior or posterior, mandibular or…
The review found no eligible studies for this question.
1 finding from 1 review
Amount of postoperative blood loss (mL) · People on continuous VKA treatment undergoing minor oral surgery or dental extractions (eligibility included DOACs and all ages; all four…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Time to feeding after surgery · Children up to 13 years of age, undergoing cleft lip repair surgery
The review found no eligible studies for this question.
1 finding from 1 review
Analgesia durationTime duration from the end of surgery to the time of first analgesic consumption. Scale from: 0 to 100. · Children up to 13 years of age, undergoing cleft lip repair surgery
1 finding from 1 review
Improvement in nutritional intake · People of any age and either sex, in any setting, with BRONJ; bisphosphonate exposure past or current; includes people with cancer and…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Heart rate, respiratory rate, and blood pressure · Children up to 13 years of age, undergoing cleft lip repair surgery
1 finding from 1 review
Ahuja 1994: no significant difference in heart rate, respiratory rate, and blood pressure between groups. Takmaz 2009: no differences in respiratory rate and blood pressure, but children in the placebo group had…
2 studies
GRADE not reported
Duration of postoperative analgesia · Children up to 13 years of age, undergoing cleft lip repair surgery
It is very uncertain whether perioperative infraorbital nerve block changes duration of postoperative analgesia (in hours) compared with placebo (sham block) (very low certainty).
1 finding from 1 review
Adverse events · People of any age and either sex, in any setting, with BRONJ; bisphosphonate exposure past or current; includes people with cancer and…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Pain measured by valid instruments (mean postoperative pain score) · Children up to 13 years of age, undergoing cleft lip repair surgery
It is very uncertain whether perioperative infraorbital nerve block changes pain measured by valid instruments (mean postoperative pain score) compared with placebo (sham block) (very low certainty).
1 finding from 1 review
Improvement of pre-existing accompanying symptoms other than pain · People of any age and either sex, in any setting, with BRONJ; bisphosphonate exposure past or current; includes people with cancer and…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Health economic measures · People of any age and either sex, in any setting, with BRONJ; bisphosphonate exposure past or current; includes people with cancer and…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Need for analgesic prescription for pain (supplemental analgesic requirements) · Children up to 13 years of age, undergoing cleft lip repair surgery
Perioperative infraorbital nerve block may leads to lower need for analgesic prescription for pain (supplemental analgesic… compared with placebo (sham block) (low certainty).
1 finding from 1 review
Quality of life · People of any age and either sex, in any setting, with BRONJ; bisphosphonate exposure past or current; includes people with cancer and…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Adverse events · Children up to 13 years of age, undergoing cleft lip repair surgery
1 finding from 1 review
Pain · People of any age and either sex, in any setting, with BRONJ; bisphosphonate exposure past or current; includes people with cancer and…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Mortality rate and cause of death · People of any age and either sex, in any setting, with BRONJ; bisphosphonate exposure past or current; includes people with cancer and…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Length of hospital stay · Children up to 13 years of age, undergoing cleft lip repair surgery
The review found no eligible studies for this question.
1 finding from 1 review
Healing of osteonecrosis - improvement ('healed' or 'improved' vs 'unchanged' or 'worse') · People of any age and either sex, in any setting, with BRONJ; bisphosphonate exposure past or current; includes people with cancer and…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found