Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

125 questions · 125 findings · 7 reviews

No studies found 44 · 35.2%GRADE not reported 1 · 0.8%Very low 52 · 41.6%Low 21 · 16.8%Moderate 7 · 5.6%High 0 · 0%

Phenobarbital vs levetiracetam

Proportion of infants who achieve seizure control after the first loading dose of ASM · neonates with EEG‐confirmed seizures

Summary of findings table ‐ Phenobarbital probably leads to higher proportion of infants who achieve seizure control after the first… compared with levetiracetam (moderate certainty).

1 finding from 1 review

Phenobarbital vs levetiracetam

Mortality before hospital discharge · neonates with clinically diagnosed seizures

Summary of findings table ‐ Phenobarbital showed no clear difference in mortality before hospital discharge compared with levetiracetam (low certainty).

1 finding from 1 review

Phenobarbital vs levetiracetam

Need for mechanical ventilation · neonates with clinically diagnosed seizures

It is very uncertain whether summary of findings table ‐ Phenobarbital changes requirement of mechanical ventilation compared with levetiracetam (very low certainty).

1 finding from 1 review

Phenobarbital vs levetiracetam

Proportion of infants who develop sedation or drowsiness · neonates with clinically diagnosed seizures

It is very uncertain whether summary of findings table ‐ Phenobarbital changes proportion of infants who develop sedation or drowsiness compared with levetiracetam (very low certainty).

1 finding from 1 review

Phenobarbital vs levetiracetam

Proportion of infants who develop epilepsy post‐discharge · neonates with clinically diagnosed seizures

It is very uncertain whether summary of findings table ‐ Phenobarbital changes proportion of infants who develop epilepsy post discharge compared with levetiracetam (very low certainty).

1 finding from 1 review

Phenobarbital vs phenytoin

Proportion of infants who achieve seizure control after maximal loading dose of ASM · neonates with EEG‐confirmed seizures

It is very uncertain whether summary of findings table ‐ Phenobarbital changes proportion of infants who achieve seizure control after the maximal… compared with phenytoin (very low certainty).

1 finding from 1 review

Phenobarbital vs phenytoin

Proportion of infants who achieve seizure control after the first loading dose of ASM · neonates with clinically diagnosed seizures

Summary of findings table ‐ Phenobarbital may leads to higher proportion of infants who achieve seizure control after first… compared with phenytoin (low certainty).

1 finding from 1 review

Phenobarbital vs levetiracetam

Proportion of infants who achieve seizure control after maximal loading dose of ASM · neonates with EEG‐confirmed seizures

Summary of findings table ‐ Phenobarbital probably leads to higher proportion of infants who achieve seizure control after the maximal… compared with levetiracetam (moderate certainty).

1 finding from 1 review

Phenobarbital vs phenytoin

Mortality before hospital discharge · neonates with clinically diagnosed seizures

It is very uncertain whether summary of findings table ‐ Phenobarbital changes mortality before hospital discharge compared with phenytoin (very low certainty).

1 finding from 1 review

Phenobarbital vs phenytoin

Need for mechanical ventilation · neonates with clinically diagnosed seizures

It is very uncertain whether summary of findings table ‐ Phenobarbital changes requirement of mechanical ventilation compared with phenytoin (very low certainty).

1 finding from 1 review

Phenobarbital vs phenytoin

Proportion of infants who develop sedation or drowsiness · neonates with clinically diagnosed seizures

It is very uncertain whether summary of findings table ‐ Phenobarbital changes proportion of infants who develop sedation or drowsiness compared with phenytoin (very low certainty).

1 finding from 1 review

Phenobarbital vs lorazepam

Proportion of infants who achieve seizure control after the first loading dose of ASM · neonates with clinically diagnosed seizures

It is very uncertain whether summary of findings table ‐ Phenobarbital changes proportion of infants who achieve seizure control after the first… compared with lorazepam (very low certainty).

1 finding from 1 review