Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

69 questions · 74 findings · 28 reviews

No studies found 11 · 14.9%GRADE not reported 6 · 8.1%Very low 10 · 13.5%Low 26 · 35.1%Moderate 20 · 27%High 1 · 1.4%

Monthly pulsed high‐dose dexamethasone vs prednisolone

≥ 1 point improvement on INCAT disability score at 12 months · patients with chronic inflammatory demyelinating polyradiculoneuropathy

Monthly pulsed high‐dose dexamethasone may leads to higher ≥ 1 point improvement on INCAT disability score at 12 months compared with oral prednisolone (low certainty).

1 finding from 1 review

Treatment route: intravenous corticosteroid vs oral corticosteroid

Mortality after discharge (1‐3 months) · exacerbations of COPD

Treatment route: intravenous corticosteroid showed no clear difference in mortality after discharge (1‐3 months) compared with oral corticosteroid (moderate certainty).

1 finding from 1 review

Treatment route: intravenous corticosteroid vs oral corticosteroid

Treatment failure Need for additional treatment · exacerbations of COPD

Treatment route: intravenous corticosteroid showed no clear difference in treatment failure Need to intensify therapy compared with oral corticosteroid (moderate certainty).

1 finding from 1 review

Treatment route: intravenous corticosteroid vs oral corticosteroid

Relapse Hospital readmission for COPD · exacerbations of COPD

Treatment route: intravenous corticosteroid showed no clear difference in relapse Hospital readmission for COPD compared with oral corticosteroid (moderate certainty).

1 finding from 1 review