Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

65 questions · 65 findings · 5 reviews · Headline outcomes only

No studies found 19 · 29.2%GRADE not reported 2 · 3.1%Very low 10 · 15.4%Low 10 · 15.4%Moderate 13 · 20%High 11 · 16.9%

Doxycycline 40 mg + azelaic acid gel vs doxycycline 40 mg + metronidazole gel

Participant‐assessed improvement in rosacea severity · Participants with rosacea

Doxycycline 40 mg + azelaic acid gel showed no clear difference in participant‐assessed improvement in rosacea severity Excellent… compared with doxycycline 40 mg + metronidazole gel (high certainty).

1 finding from 1 review