Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

185 questions · 193 findings · 7 reviews · Orthodontics

No studies found 44 · 22.8%GRADE not reported 99 · 51.3%Very low 26 · 13.5%Low 18 · 9.3%Moderate 6 · 3.1%High 0 · 0%

Facemask vs no intervention

Overjet · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Facemask led to higher overjet compared with untreated control (no treatment); GRADE not reported.

3 findings from 1 review

Facemask with rapid maxillary expansion (RME) vs Facemask only

Wits appraisal · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Facemask with rapid maxillary expansion (RME) showed no clear difference in wits appraisal compared with facemask only; GRADE not reported.

1 finding from 1 review

Facemask with rapid maxillary expansion (RME) vs Reverse chin cup

ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Facemask with rapid maxillary expansion (RME) showed no clear difference in ANB compared with reverse chin cup; GRADE not reported.

1 finding from 1 review

Tandem traction bow appliance vs no intervention

ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Tandem traction bow appliance led to higher ANB compared with untreated control (no treatment); GRADE not reported.

1 finding from 1 review

Facemask vs no intervention

Self-esteem (Piers-Harris self-concept scale) · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Facemask showed no clear difference in self-esteem (Piers-Harris self-concept scale) compared with untreated control (no treatment); GRADE not reported.

3 findings from 1 review

Facemask with rapid maxillary expansion (RME) vs Facemask with alternating rapid maxillary expansion and constriction (Alt-RAMEC)

ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Facemask with rapid maxillary expansion (RME) showed no clear difference in ANB compared with facemask with alternating rapid maxillary expansion and constriction… (low certainty).

1 finding from 1 review

Chin cup (600 g force) vs Chin cup (300 g force)

Wits appraisal · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Chin cup (600 g force) showed no clear difference in wits appraisal compared with chin cup (300 g force); GRADE not reported.

1 finding from 1 review

Hybrid Hyrax (RME) with miniscrews and Class III elastics vs Conventional Hyrax (RME) with miniscrews and Class III elastics

Overjet · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Hybrid Hyrax (RME) with miniscrews and Class III elastics showed no clear difference in overjet compared with conventional Hyrax (RME) with miniscrews and Class III elastics; GRADE not reported.

1 finding from 1 review

Facemask with rapid maxillary expansion (RME) vs Mini maxillary protractor

Overjet · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Facemask with rapid maxillary expansion (RME) showed no clear difference in overjet compared with mini maxillary protractor; GRADE not reported.

1 finding from 1 review

Facemask (RME) or modified facemask vs Other non-surgical orthodontic treatments (mini maxillary protractor, Pushing Splints, modified tandem, Reverse Forsus, reverse Twin Block, reverse chin cup, tongue appliance, Frankel III)

ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

It is very uncertain whether facemask (RME) or modified facemask changes ANB compared with other non-surgical orthodontic treatments (mini maxillary… (very low certainty).

1 finding from 1 review

Facemask (RME) or modified facemask vs Surgically-anchored appliance (miniscrews or miniplates)

Overjet · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

It is very uncertain whether facemask (RME) or modified facemask changes overjet compared with surgically-anchored appliance (miniscrews or miniplates) (very low certainty).

1 finding from 1 review

Facemask with rapid maxillary expansion (RME) vs Facemask with alternating rapid maxillary expansion and constriction (Alt-RAMEC)

Overjet · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

The review found no eligible studies for this question.

1 finding from 1 review

Facemask with rapid maxillary expansion (RME) vs Facemask with alternating rapid maxillary expansion and constriction (Alt-RAMEC)

A-Nasion perpendicular (A-NPerp) · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Facemask with rapid maxillary expansion (RME) led to higher A-Nasion perpendicular (A-NPerp) compared with facemask with alternating rapid maxillary expansion and constriction…; GRADE not reported.

1 finding from 1 review

Facemask with rapid maxillary expansion (RME) vs Tongue appliance

ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Facemask with rapid maxillary expansion (RME) showed no clear difference in ANB compared with tongue appliance; GRADE not reported.

1 finding from 1 review

Facemask with rapid maxillary expansion (RME) vs Modified tandem appliance

ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Facemask with rapid maxillary expansion (RME) showed no clear difference in ANB compared with modified tandem appliance; GRADE not reported.

1 finding from 1 review

Surgically-anchored orthodontic treatment (miniplates) vs no intervention

Perceived need for surgery in adulthood · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

The review found no eligible studies for this question.

1 finding from 1 review

Orthodontic removable traction appliance (ORTA) vs no intervention

Overjet · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Orthodontic removable traction appliance (ORTA) led to higher overjet compared with untreated control (no treatment); GRADE not reported.

1 finding from 1 review

Non-surgical orthodontic treatment (any: facemask, chin cup, tandem traction bow, mandibular headgear, ORTA, reverse Twin Block, Reverse Forsus) vs no treatment

Wits appraisal · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Non-surgical orthodontic treatment (any: facemask, chin cup, tandem… led to higher wits appraisal compared with no treatment; GRADE not reported.

1 finding from 1 review

Facemask with rapid maxillary expansion (RME) vs Pushing Splints

Wits appraisal · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Facemask with rapid maxillary expansion (RME) showed no clear difference in wits appraisal compared with pushing Splints; GRADE not reported.

1 finding from 1 review

Facemask vs no intervention

ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Facemask probably leads to higher ANB compared with untreated control (no treatment) (moderate certainty).

3 findings from 1 review