Efficacy: response (categorical) YMRS change ≥ 50% from baseline to end of study · acute mania
Lithium leads to higher efficacy: response (categorical) YMRS change ≥ 50% from baseline to… compared with topiramate (high certainty).
1 finding from 1 review
Efficacy: response (continuous) YMRS change by ≥ 50% at end of study · acute mania
The review found no eligible studies for this question.
1 finding from 1 review
Lithium for acute mania 2019 · Cochrane Headline outcomes only no estimate extracted
Studies not reported
No studies found
Remission · acute mania
Lithium leads to higher efficacy: remission (categorical) YMRS ≤ 12 at end of study compared with topiramate (high certainty).
1 finding from 1 review
Acceptability: total withdrawals · acute mania
Lithium showed no clear difference in acceptability: total withdrawals compared with topiramate (high certainty).
1 finding from 1 review
Efficacy: response (categorical) YMRS change ≥ 50% from baseline to end of study · acute mania
The review found no eligible studies for this question.
1 finding from 1 review
Lithium for acute mania 2019 · Cochrane Headline outcomes only no estimate extracted
Studies not reported
No studies found
Efficacy: response (continuous) CGI change from baseline to end of study · acute mania
1 finding from 1 review
Weight gain · acute mania
Lithium showed no clear difference in adverse event: weight gain compared with placebo (moderate certainty).
1 finding from 1 review
Efficacy : remission (categorical) YMRS ≤ 12 at end of study · acute mania
The review found no eligible studies for this question.
1 finding from 1 review
Lithium for acute mania 2019 · Cochrane Headline outcomes only no estimate extracted
Studies not reported
No studies found
Acceptability: total withdrawals · acute mania
The review found no eligible studies for this question.
1 finding from 1 review
Lithium for acute mania 2019 · Cochrane Headline outcomes only no estimate extracted
Studies not reported
No studies found
Adverse events · acute mania
The review found no eligible studies for this question.
1 finding from 1 review
Lithium for acute mania 2019 · Cochrane Headline outcomes only no estimate extracted
Studies not reported
No studies found
Efficacy: response (categorical) YMRS change ≥ 50% from baseline to end of study · acute mania
The review found no eligible studies for this question.
1 finding from 1 review
Lithium for acute mania 2019 · Cochrane Headline outcomes only no estimate extracted
Studies not reported
No studies found
Efficacy: response (continuous) MRS mean change from baseline to end of study · acute mania
1 finding from 1 review
Remission · acute mania
The review found no eligible studies for this question.
1 finding from 1 review
Lithium for acute mania 2019 · Cochrane Headline outcomes only no estimate extracted
Studies not reported
No studies found
Acceptability: total withdrawals · acute mania
The review found no eligible studies for this question.
1 finding from 1 review
Lithium for acute mania 2019 · Cochrane Headline outcomes only no estimate extracted
Studies not reported
No studies found
Adverse events · acute mania
The review found no eligible studies for this question.
1 finding from 1 review
Lithium for acute mania 2019 · Cochrane Headline outcomes only no estimate extracted
Studies not reported
No studies found
Efficacy: response (categorical) YMRS/MRS/BPRS change by ≥ 50% at end of study · acute mania
Lithium leads to higher efficacy: response (categorical) YMRS/MRS/BPRS change by ≥ 50% at… compared with all antimanic agents (high certainty).
1 finding from 1 review
Efficacy: response (continuous) YMRS/BPRS change from baseline to end of study · acute mania
1 finding from 1 review
Efficacy: response (categorical) YMRS/SADS‐C decrease ≥ 50% by end of study · acute mania
Lithium showed no clear difference in efficacy: response (categorical) YMRS/SADS‐C decrease ≥ 50% by end… compared with valproate (moderate certainty).
1 finding from 1 review
Remission · acute mania
The review found no eligible studies for this question.
1 finding from 1 review
Lithium for acute mania 2019 · Cochrane Headline outcomes only no estimate extracted
Studies not reported
No studies found
Acceptability: total withdrawals · acute mania
Lithium showed no clear difference in acceptability: total withdrawals compared with all antimanic agents (high certainty).
1 finding from 1 review