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What do systematic reviews say?

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Evidence found and GRADE certainty

65 questions · 73 findings · 16 reviews

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No studies found 8 · 11%GRADE not reported 19 · 26%Very low 10 · 13.7%Low 11 · 15.1%Moderate 14 · 19.2%High 11 · 15.1%

Intervention not reported

Death at any time in trial period case mortality count · Patients with acute traumatic brain injury

The intervention probably leads to lower death at any time in trial period case mortality count (moderate certainty).

1 finding from 1 review

Intervention not reported

Favourable outcome GOS <9 or similar · Patients with acute traumatic brain injury

The intervention showed no clear difference in favourable outcome GOS <9 or similar; GRADE not reported.

1 finding from 1 review

Intervention not reported

Mean improvement in pure‐tone average hearing threshold across all frequencies Decibels Scale from: 0 to 120 · patients with idiopathic sudden sensorineural hearing loss or tinnitus
1 finding from 1 review

Intervention not reported

More than 50% improvement in pure‐tone average threshold Risk ratio · patients with idiopathic sudden sensorineural hearing loss or tinnitus

The intervention showed no clear difference in more than 50% improvement in pure‐tone average threshold Risk ratio (moderate certainty).

1 finding from 1 review

Intervention not reported

More than 25% improvement in pure‐tone average threshold Risk ratio · patients with idiopathic sudden sensorineural hearing loss or tinnitus

The intervention probably leads to higher more than 25% improvement in pure‐tone average threshold Risk ratio (moderate certainty).

1 finding from 1 review