Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

86 questions · 86 findings · 5 reviews

No studies found 29 · 33.7%GRADE not reported 0 · 0%Very low 36 · 41.9%Low 12 · 14%Moderate 5 · 5.8%High 4 · 4.7%

Gemcitabine plus oxaliplatin vs 5‐fluorouracil plus cisplatin plus radiotherapy

All‐cause mortality at 1 year · people with advanced biliary tract carcinomas

It is very uncertain whether gemcitabine plus oxaliplatin changes all‐cause mortality at 1 year compared with 5‐fluorouracil plus cisplatin plus radiotherapy (very low certainty).

1 finding from 1 review

Gemcitabine plus oxaliplatin vs 5‐fluorouracil plus cisplatin plus radiotherapy

Serious adverse events · people with advanced biliary tract carcinomas

It is very uncertain whether gemcitabine plus oxaliplatin changes serious adverse events compared with 5‐fluorouracil plus cisplatin plus radiotherapy (very low certainty).

1 finding from 1 review

Closed‐system transfer device plus safe handling vs safe handling alone

Gemcitabine · healthcare staff who handle infusional hazardous drugs

It is very uncertain whether closed‐system transfer device plus safe handling changes gemcitabine compared with safe handling alone (very low certainty).

1 finding from 1 review