Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

65 questions · 82 findings · 9 reviews

No studies found 12 · 14.6%GRADE not reported 57 · 69.5%Very low 9 · 11%Low 0 · 0%Moderate 4 · 4.9%High 0 · 0%

1400/250 ppm F (amine F/SnF2) toothpaste + mouthrinse, daily vs 1400/250 ppm F (NaF) toothpaste + mouthrinse, daily

White spot lesion index (mean change from baseline) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

It is very uncertain whether 1400/250 ppm F (amine F/SnF2) toothpaste + mouthrinse, daily changes white spot lesion index (mean change from baseline) compared with 1400/250 ppm F (NaF) toothpaste + mouthrinse, daily (very low certainty).

1 finding from 1 review

1400/250 ppm F (amine F/SnF2) toothpaste + mouthrinse, daily vs 1400/250 ppm F (NaF) toothpaste + mouthrinse, daily

Plaque index (PI) / oral hygiene · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

It is very uncertain whether 1400/250 ppm F (amine F/SnF2) toothpaste + mouthrinse, daily changes visible plaque index (mean change from baseline) compared with 1400/250 ppm F (NaF) toothpaste + mouthrinse, daily (very low certainty).

1 finding from 1 review

Patient-used 250 ppm F mouthrinse (100 ppm amine F/150 ppm NaF), daily vs 0 ppm F placebo mouthrinse, daily

Adverse effects · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

The review found no eligible studies for this question.

1 finding from 1 review

Patient-used 250 ppm F mouthrinse (100 ppm amine F/150 ppm NaF), daily vs 0 ppm F placebo mouthrinse, daily

Number of participants with more severe DLs (severity of DLs) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

The review found no eligible studies for this question.

1 finding from 1 review

Patient-used 250 ppm F mouthrinse (100 ppm amine F/150 ppm NaF), daily vs 0 ppm F placebo mouthrinse, daily

Number of participants with new demineralised lesions (DLs) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

It is very uncertain whether patient-used 250 ppm F mouthrinse (100 ppm amine F/150 ppm NaF), daily changes number of participants with new demineralised lesions (DLs) compared with 0 ppm F placebo mouthrinse, daily (very low certainty).

1 finding from 1 review