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Evidence found and GRADE certainty

77 questions · 77 findings · 5 reviews · All outcomes

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No studies found 13 · 16.9%GRADE not reported 27 · 35.1%Very low 22 · 28.6%Low 15 · 19.5%Moderate 0 · 0%High 0 · 0%

Topical clobetasol propionate vs Topical tacrolimus

Pain resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether topical clobetasol propionate changes pain resolution compared with topical tacrolimus (very low certainty).

1 finding from 1 review

Intralesional betamethasone vs intralesional injections of triamcinolone acetonide

Pain (mean score) · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

Intralesional betamethasone showed no clear difference in pain (mean score) compared with intralesional triamcinolone acetonide (low certainty).

1 finding from 1 review

Topical clobetasol propionate vs Topical ciclosporin

Adverse effects · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether topical clobetasol propionate changes adverse effects compared with topical ciclosporin (very low certainty).

1 finding from 1 review

Systemic (oral) betamethasone vs Topical triamcinolone acetonide paste

Pain resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether systemic (oral) betamethasone changes pain resolution compared with topical triamcinolone acetonide paste (very low certainty).

1 finding from 1 review

Clobetasol propionate ointment vs Low-level laser therapy (LLLT)

Pain (mean score) · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether clobetasol propionate ointment changes pain (mean score) compared with low-level laser therapy (LLLT) (very low certainty).

1 finding from 1 review

Clobetasol propionate 0.025% microspheres vs Clobetasol propionate 0.025% ointment

Clinical score · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

Clobetasol propionate 0.025% microspheres showed no clear difference in clinical score compared with clobetasol propionate 0.025% ointment; GRADE not reported.

1 finding from 1 review

Clobetasol propionate ointment vs Low-level laser therapy (LLLT)

Clinical score · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether clobetasol propionate ointment changes clinical score compared with low-level laser therapy (LLLT) (very low certainty).

1 finding from 1 review

Topical triamcinolone acetonide vs pimecrolimus 1%

Pain (mean VAS score) · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

Topical triamcinolone acetonide showed no clear difference in pain (mean VAS score) compared with topical pimecrolimus; GRADE not reported.

1 finding from 1 review

Topical triamcinolone acetonide vs Photodynamic therapy

Pain (mean score) · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether topical triamcinolone acetonide changes pain (mean score) compared with photodynamic therapy (very low certainty).

1 finding from 1 review

Clobetasol propionate ointment vs Clobetasol propionate 0.025% ointment

Pain (mean score) · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

Clobetasol propionate 0.05% ointment showed no clear difference in pain (mean score) compared with clobetasol propionate 0.025% ointment (low certainty).

1 finding from 1 review

Clobetasol propionate ointment vs Low-level laser therapy (LLLT)

Clinical resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether clobetasol propionate ointment changes clinical resolution compared with low-level laser therapy (LLLT) (very low certainty).

1 finding from 1 review

Clobetasol propionate ointment vs Triamcinolone acetonide ointment

Clinical resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

Clobetasol propionate ointment may leads to higher clinical resolution compared with triamcinolone acetonide ointment (low certainty).

1 finding from 1 review