Antidepressants vs any other pharmacological intervention
Depression response (early phase, < 5 weeks) · women of any age, with PND up to 12 months
1 finding from 1 review
- no estimate extractedStudies not reportedLow
Findings
What do systematic reviews say?
406 questions · 416 findings · 20 reviews · Common Mental Disorders
No studies found 73 · 17.5%GRADE not reported 9 · 2.2%Very low 144 · 34.6%Low 123 · 29.6%Moderate 59 · 14.2%High 8 · 1.9%
Antidepressants vs any other pharmacological intervention
Depression severity (acute phase, 5 ≤ 12 weeks) · women of any age, with PND up to 12 months
1 finding from 1 review
- no estimate extractedStudies not reportedVery low
Antidepressants vs placebo
Adverse events · women of any age, with PND up to 12 months
Antidepressants may leads to lower adverse events compared with placebo (low certainty).
1 finding from 1 review
- no estimate extractedStudies not reportedLow
Antidepressants vs any other pharmacological intervention
Acceptability ‐ total dropouts · women of any age, with PND up to 12 months
It is very uncertain whether antidepressants changes treatment acceptability ‐dropouts compared with any other pharmacological intervention (very low certainty).
1 finding from 1 review
- RR 1.74 [0.99, 3.06]Studies not reportedVery low
Antidepressants vs any other pharmacological intervention
Child‐related outcomes · women of any age, with PND up to 12 months
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Antidepressants vs any complementary medicine
Depression response (acute phase, 5 ≤ 12 weeks) · women of any age, with PND up to 12 months
It is very uncertain whether antidepressants changes depression response (acute phase, 5 ≤ 12 weeks) compared with any complementary medicine (very low certainty).
1 finding from 1 review
- RR 1.23 [0.71, 2.12]Studies not reportedVery low
Antidepressants vs any complementary medicine
Depression remission · women of any age, with PND up to 12 months
It is very uncertain whether antidepressants changes depression remission (acute phase, 5 ≤ 12 weeks) compared with any complementary medicine (very low certainty).
1 finding from 1 review
- RR 1.17 [0.44, 3.09]Studies not reportedVery low
Antidepressants vs any complementary medicine
Adverse events · women of any age, with PND up to 12 months
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Antidepressants vs any complementary medicine
Depression severity · women of any age, with PND up to 12 months
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Antidepressants vs any complementary medicine
Secondary outcome: acceptability of treatment · women of any age, with PND up to 12 months
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Antidepressants vs any complementary medicine
Child‐related outcomes · women of any age, with PND up to 12 months
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Antidepressants vs placebo
Depression severity (acute phase, 5 ≤ 12 weeks) · women of any age, with PND up to 12 months
2 findings from 1 review
- no estimate extractedStudies not reportedLow
- no estimate extractedStudies not reportedLow
Antidepressants vs placebo
Acceptability ‐ total dropouts · women of any age, with PND up to 12 months
Antidepressants showed no clear difference in treatment acceptability ‐ dropouts compared with placebo (low certainty).
1 finding from 1 review
- RR 1.1 [0.74, 1.64]Studies not reportedLow
Antidepressants vs placebo
Child‐related outcomes · women of any age, with PND up to 12 months
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Antidepressants vs treatment
Depression response or remission (acute phase, 5 ≤ 12 weeks) · women of any age, with PND up to 12 months
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Antidepressants vs treatment
Adverse events · women of any age, with PND up to 12 months
1 finding from 1 review
- no estimate extractedStudies not reportedVery low
Antidepressants vs a combination of medications
Severity/intensity of MUPS (post‐treatment score on self report scales) Different self report and clinician‐rated scales (SOMS‐7, SCL‐90 Somatisation Score) · somatoform disorders in adults
1 finding from 1 review
- Pharmacological interventions for somatoform disorders in adults 2014 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 107 participantsLow
Antidepressants vs a combination of medications
Acceptability · somatoform disorders in adults
Antidepressants showed no clear difference in acceptability (all‐cause drop‐outs4) compared with a combination of medications (low certainty).
1 finding from 1 review
- Pharmacological interventions for somatoform disorders in adults 2014 · Cochrane Headline outcomes onlyRR 0.8 [0.25, 2.52]2 studies · 118 participantsLow
Antidepressants vs a combination of medications
Anxiety · somatoform disorders in adults
1 finding from 1 review
- Pharmacological interventions for somatoform disorders in adults 2014 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 107 participantsVery low
Antidepressants vs a combination of medications
Depression (post‐treatment score on self report and clinician‐rated scales) Different self report and clinician‐rated scales (HDRS, BDI) · somatoform disorders in adults
1 finding from 1 review
- Pharmacological interventions for somatoform disorders in adults 2014 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 107 participantsVery low