Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

613 questions · 624 findings · 42 reviews · Headline outcomes only

No studies found 85 · 13.6%GRADE not reported 37 · 5.9%Very low 211 · 33.8%Low 181 · 29%Moderate 92 · 14.7%High 18 · 2.9%

Antidepressants vs placebo

Depression response (acute phase, 5 ≤ 12 weeks) · women of any age, with PND up to 12 months

Antidepressants showed no clear difference in depression response (acute, 5 ≤ 12 weeks) compared with placebo (low certainty).

1 finding from 1 review

Antidepressants vs treatment

Depression remission · women of any age, with PND up to 12 months

It is very uncertain whether antidepressants changes depression remission (early phase, < 5 weeks) compared with treatment (very low certainty).

1 finding from 1 review

Antidepressants vs treatment

Dropout · women of any age, with PND up to 12 months

It is very uncertain whether antidepressants changes treatment acceptability ‐ dropouts (early phase, < 5 weeks) compared with treatment (very low certainty).

1 finding from 1 review