Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

65 questions · 65 findings · 5 reviews · Musculoskeletal

No studies found 31 · 47.7%GRADE not reported 1 · 1.5%Very low 0 · 0%Low 12 · 18.5%Moderate 14 · 21.5%High 7 · 10.8%

Febuxostat 120 mg/day vs allopurinol

Withdrawals due to adverse events · people with chronic gout

Febuxostat 120 mg/day showed no clear difference in discontinuations due to adverse events compared with allopurinol (high certainty).

1 finding from 1 review