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What do systematic reviews say?

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Evidence found and GRADE certainty

1,835 questions · 1,886 findings · 74 reviews · Skin

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No studies found 542 · 28.7%GRADE not reported 130 · 6.9%Very low 326 · 17.3%Low 434 · 23%Moderate 348 · 18.5%High 106 · 5.6%

Tonsillectomy vs no intervention

Proportion of participants with adverse events and severe adverse events · people with chronic plaque psoriasis

It is very uncertain whether tonsillectomy changes proportion of participants with adverse events and severe adverse… compared with no intervention (very low certainty).

1 finding from 1 review

Tonsillectomy vs no intervention

Proportion of participants achieving clear or almost clear skin (PASI 90 to 100 or PGA 0 to 1) · people with chronic plaque psoriasis

It is very uncertain whether tonsillectomy changes proportion of participants achieving clear or almost clear skin… compared with no intervention (very low certainty).

1 finding from 1 review

Penicillin vs no treatment

Proportion of participants achieving clear or almost clear skin (PASI 90 to 100 or PGA 0 to 1) · guttate psoriasis

It is very uncertain whether penicillin changes proportion of participants achieving clear or almost clear skin… compared with no treatment (very low certainty).

1 finding from 1 review