Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,908 questions · 3,101 findings · 509 reviews

No studies found 571 · 18.4%GRADE not reported 358 · 11.5%Very low 723 · 23.3%Low 854 · 27.5%Moderate 489 · 15.8%High 106 · 3.4%

Routine vaginal examination vs routine rectal examination

Admission to neonatal intensive care unit · pregnant women in labour at term

It is very uncertain whether routine vaginal examination changes admission to neonatal intensive care unit№ of participants: 307(1 RCT) compared with routine rectal examination (very low certainty).

1 finding from 1 review

Ocrelizumab vs placebo

Number of participants with new or enlarging T2‐hyperintense lesions on MRI · primary progressive multiple sclerosis

The review found no eligible studies for this question.

1 finding from 1 review

Ocrelizumab vs interferon beta‐1a

Number of participants with new or enlarging T2‐hyperintense lesions on MRI · patients with relapsing‐remitting multiple sclerosis

Ocrelizumab may leads to lower number of participants with new or enlarging T2‐hyperintense lesions… compared with interferon beta‐1a (low certainty).

1 finding from 1 review