Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,289 questions · 2,331 findings · 195 reviews · Pregnancy and Childbirth

No studies found 480 · 20.6%GRADE not reported 288 · 12.4%Very low 467 · 20%Low 630 · 27%Moderate 338 · 14.5%High 128 · 5.5%

Oral magnesium vs placebo/no treatment

Frequency: 50% reduction in number of leg cramps · treating leg cramps in pregnancy

Oral magnesium may leads to higher frequency: 50% reduction in number of leg cramps compared with placebo/no treatment (low certainty).

1 finding from 1 review

Oral magnesium vs placebo/no treatment

Intensity of pain during treatment: mean total scale points The degree of pain was noted in the form, on a scale from 0 to 4 measured over 4 days and nights (0 = no pain, 1 = light pain, 2 = medium pain, 3=strong pain, 4=extreme pain) · treating leg cramps in pregnancy
1 finding from 1 review

Oral magnesium vs placebo/no treatment

At least 50% reduction in pain · treating leg cramps in pregnancy

It is very uncertain whether oral magnesium changes intensity of pain: 50% reduction in pain score 100‐mm visual… compared with placebo/no treatment (very low certainty).

1 finding from 1 review

Oral magnesium vs placebo/no treatment

Duration of leg cramps: persisting symptoms after night‐time cramps Always · treating leg cramps in pregnancy

Oral magnesium may leads to lower duration of leg cramps: persisting symptoms after night‐time cramps… compared with placebo/no treatment (low certainty).

1 finding from 1 review

Oral magnesium vs placebo/no treatment

Duration of leg cramps: persisting symptoms after night‐time cramps Sometimes · treating leg cramps in pregnancy

It is very uncertain whether oral magnesium changes duration of leg cramps: persisting symptoms after night‐time cramps… compared with placebo/no treatment (very low certainty).

1 finding from 1 review

Oral magnesium vs placebo/no treatment

Composite outcome: symptoms of leg cramps (intensity and frequency) Partial improvement: decrease in intensity and frequency · treating leg cramps in pregnancy

It is very uncertain whether oral magnesium changes composite outcome: symptoms of leg cramps (intensity and frequency)… compared with placebo/no treatment (very low certainty).

1 finding from 1 review

Setting of BP measurement: self‐measurement vs conventional clinic measurement

Neonatal unit admission · pregnant women with chronic or gestational hypertension

Setting of BP measurement: self‐measurement showed no clear difference in neonatal unit admission compared with conventional clinic measurement (low certainty).

1 finding from 1 review