Findings

What do systematic reviews say?

1,171 questions · 1,373 findings · 60 reviews · Dental caries

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No studies found 282 · 20.5%GRADE not reported 606 · 44.1%Very low 257 · 18.7%Low 160 · 11.7%Moderate 66 · 4.8%High 2 · 0.1%

Mineral trioxide aggregate (MTA) vs IRM (intermediate restorative material)

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth

The review found no eligible studies for this question.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
Listed as a pulpectomy comparison; no extractable outcome data reported in this version
0 studies
No studies found

Low‐level laser therapy vs Formocresol (FC)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Low-level laser therapy (LLLT) showed no clear difference in radiological failure compared with formocresol (FC); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
6 and 12 months
RR 7.00 [0.39, 124.83]
1 study · 30 participants
GRADE not reported

Vitapex (calcium hydroxide/iodoform) vs RC Fill

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
6, 12 and 30 months
No clinical failure in any participant at 6/12/30 months (Pramila 2016); not estimable
1 study · 86 participants
GRADE not reported

Aloe vera vs Mineral trioxide aggregate (MTA)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Aloe vera led to higher radiological failure compared with mineral trioxide aggregate (MTA); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
6 and 12 months
RR 28.00 [4.07, 192.79]
1 study · 60 participants
GRADE not reported

Mineral trioxide aggregate (MTA) vs Zinc oxide and eugenol (ZOE)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Mineral trioxide aggregate (MTA) showed no clear difference in clinical failure compared with zinc oxide and eugenol (ZOE); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
24 months
RR 0.20 [0.03, 1.59]
1 study · 50 participants
GRADE not reported

Portland cement (PC) vs Full strength formocresol (FC)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Portland cement (PC) showed no clear difference in radiological failure compared with full strength formocresol (FC); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
24 months
RR 0.80 [0.23, 2.73]
1 study · 70 participants
GRADE not reported

Total-etching 36% phosphoric acid + acetone-based total-etch adhesive vs Non-rinse conditioner + acetone-based total-etch adhesive

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether total-etching 36% phosphoric acid + acetone-based total-etch adhesive changes radiological failure compared with non-rinse conditioner + acetone-based total-etch adhesive (very low certainty).

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
24 months
RR 7.00 [0.38, 127.33]
1 study · 40 participants
Very low

Mineral trioxide aggregate (MTA) vs Mineral trioxide aggregate (MTA) + sodium hypochlorite (NaOCl)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Mineral trioxide aggregate (MTA) showed no clear difference in radiological failure compared with mineral trioxide aggregate (MTA) + sodium hypochlorite (NaOCl); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
6 and 12 months
RR 0.33 [0.01, 7.88]
1 study · 62 participants
GRADE not reported

Mineral trioxide aggregate (MTA) vs Ferric sulphate (FS)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Mineral trioxide aggregate (MTA) showed no clear difference in radiological failure compared with ferric sulphate (FS) (low certainty).

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
24 months
RR 0.58 [0.25, 1.36]
3 studies · 130 participants
Low

Calcium hydroxide + sodium hypochlorite (NaOCl) vs Calcium hydroxide (CH)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Calcium hydroxide + sodium hypochlorite (NaOCl) showed no clear difference in radiological failure compared with calcium hydroxide (CH); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 0.63 [0.23, 1.70]
1 study · 62 participants
GRADE not reported

Self-etch adhesive + acetone-based total-etch adhesive vs Total-etching 36% phosphoric acid + acetone-based total-etch adhesive

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether self-etch adhesive + acetone-based total-etch adhesive changes radiological failure compared with total-etching 36% phosphoric acid + acetone-based total-etch adhesive (very low certainty).

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
24 months
RR 0.33 [0.04, 2.94]
1 study · 40 participants
Very low

Sodium hypochlorite (NaOCl) vs 1:5 diluted formocresol (FC)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Sodium hypochlorite (NaOCl) showed no clear difference in radiological failure compared with 1:5 diluted formocresol (FC); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 1.86 [0.52, 6.59]
2 studies · 150 participants
GRADE not reported

Calcium hydroxide cement (Dycal) vs Calcium sulphate hemihydrate (DentoGen)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether calcium hydroxide cement (Dycal) changes radiological failure compared with calcium sulphate hemihydrate (DentoGen) (very low certainty).

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 1.67 [0.46, 6.06]
1 study · 40 participants
Very low

Biodentine vs Propolis

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Biodentine showed no clear difference in clinical failure compared with propolis; GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
6 months
RR 0.33 [0.01, 7.81]
1 study · 50 participants
GRADE not reported

Vitapex (calcium hydroxide/iodoform) vs Sealapex (eugenol-free calcium hydroxide)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Vitapex (calcium hydroxide/iodoform) showed no clear difference in clinical failure compared with sealapex (eugenol-free calcium hydroxide); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 0.20 [0.01, 3.92]
1 study · 40 participants
GRADE not reported

Zinc oxide and eugenol (ZOE) vs Formocresol (FC)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Zinc oxide and eugenol (ZOE) showed no clear difference in radiological failure compared with formocresol (FC); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
24 months
RR 1.67 [0.71, 3.89]
1 study · 50 participants
GRADE not reported

Diode laser vs electrosurgery

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Diode laser showed no clear difference in radiological failure compared with electrosurgery (low certainty).

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
6 months
RR 0.64 [0.19, 2.18]
2 studies · 50 participants
Low

Non-rinse conditioner + acetone-based total-etch adhesive vs Acetone-based total-etch adhesive

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether non-rinse conditioner + acetone-based total-etch adhesive changes radiological failure compared with acetone-based total-etch adhesive (very low certainty).

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 and 24 months
RR 3.00 [0.13, 69.52]
1 study · 40 participants
Very low

Sealapex (eugenol-free calcium hydroxide) vs Zinc oxide and eugenol (ZOE)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Sealapex (eugenol-free calcium hydroxide) showed no clear difference in clinical failure compared with zinc oxide and eugenol (ZOE); GRADE not reported.

1 finding from 1 review

Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
12 months
RR 5.00 [0.26, 98.00]
1 study · 40 participants
GRADE not reported

ART using resin-modified glass ionomer cement (RM-GIC) vs Conventional treatment using RM-GIC

Participant experience · Older adults with root caries in permanent (mature) teeth (mean age 75 years)

The review found no eligible studies for this question.

1 finding from 1 review

Atraumatic restorative treatment versus conventional restorative treatment for managing dental caries 2017 · Cochrane All outcomes
No studies reported on participant experience for this comparison.
0 studies
No studies found