Quality of life or patient satisfaction · Adolescents/teenagers undergoing orthodontic treatment
Experimental chewing adjuncts (bite wafers or chewing gum) led to lower quality of life or patient satisfaction compared with no chewing gum, placebo, or control (no adjunct); GRADE not reported.
1 finding from 1 review
Adverse effects: mild headache · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether anticonvulsants (gabapentin + alpha lipoic acid) changes adverse effects: mild headache compared with placebo (very low certainty).
1 finding from 1 review
Adverse events · Children up to 13 years of age, undergoing cleft lip repair surgery
1 finding from 1 review
Adverse effects of pain treatment · Adolescents and adults undergoing orthodontic treatment
The review found no eligible studies for this question.
1 finding from 1 review
Quality of life (validated questionnaire) · Children with obstructive sleep apnoea (aged 15 years or younger)
The review found no eligible studies for this question.
1 finding from 1 review
Somnolence · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether antidepressants (trazodone 200 mg/day) changes adverse effects: drowsiness compared with placebo (very low certainty).
1 finding from 1 review
Relief of burning/discomfort (symptom relief; pain intensity) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether topical treatments (lactoperoxidase oral rinse / Biotene) changes relief of burning/discomfort (symptom relief; pain intensity) compared with placebo (very low certainty).
1 finding from 1 review
Change in QoL - depression (surrogate marker) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether benzodiazepines (systemic clonazepam) changes change in QoL - depression (surrogate marker) compared with placebo (very low certainty).
1 finding from 1 review
Adverse effects: palpitations · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether antidepressants (trazodone 200 mg/day) changes adverse effects: palpitations compared with placebo (very low certainty).
1 finding from 1 review
Somnolence · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether dietary supplements (alpha lipoic acid +/- adjunctive ingredients) changes adverse effects: drowsiness compared with placebo (very low certainty).
1 finding from 1 review
QoL · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether electromagnetic radiation (low-level laser therapy) changes change in quality of life (QoL) compared with placebo (very low certainty).
1 finding from 1 review
Improvement of histological features (not improved) · People with a diagnosis of oral leukoplakia
1 finding from 1 review
Change in QoL - depression (surrogate marker) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether dietary supplements (lycopene) changes change in QoL - depression (surrogate marker) compared with placebo (very low certainty).
1 finding from 1 review
Pain · People of any age and either sex, in any setting, with BRONJ; bisphosphonate exposure past or current; includes people with cancer and…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Economic evaluation (costs) · Children with obstructive sleep apnoea (aged 15 years or younger)
The review found no eligible studies for this question.
1 finding from 1 review
Surgical removal of the lesion (surgical excision, laser surgery, cryotherapy) vs Placebo or no treatment
Outcome not reported · People with a diagnosis of oral leukoplakia
The review found no eligible studies for this question.
1 finding from 1 review
'We did not identify any RCTs that compared surgical treatments with placebo or no treatment.' Three surgical RCTs were found (Chee 2013, Lopez-Jornet 2013, Schwarz 2005) but all excluded because they did not include a…
Studies not reported
No studies found
Improvement of histological features (not improved) · People with a diagnosis of oral leukoplakia
It is very uncertain whether topical bleomycin changes improvement of histological features (not improved) compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Adverse effects: spasmophilia · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether benzodiazepines (topical clonazepam) changes adverse effects: spasmophilia compared with placebo (very low certainty).
1 finding from 1 review
Mortality rate and cause of death · People of any age and either sex, in any setting, with BRONJ; bisphosphonate exposure past or current; includes people with cancer and…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Improvement of the overbite and overjet (plaster models) · Children with obstructive sleep apnoea (aged 15 years or younger)
The review found no eligible studies for this question.
1 finding from 1 review