What do systematic reviews say?

Surface‐modified vs standard catheter

Surface‐modified showed no clear difference in vascular access complications compared with standard double‐lumen catheter with identical geometry and flow design (low certainty).

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  RR 0.33 [0.09, 1.2]
  1 study · 236 participants
  Low

Polyethylenimine‐treated membrane (AN69ST) vs other membranes

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 56 participants
  Low

Polyethylenimine‐treated membrane (AN69ST) vs other membranes

The review found no eligible studies for this question.

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Polyethylenimine‐treated membrane (AN69ST) vs other membranes

The review found no eligible studies for this question.

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Polyethylenimine‐treated membrane (AN69ST) vs other membranes

The review found no eligible studies for this question.

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Flat plate vs hollow fibre filter of the same membrane type

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 38 participants
  Very low

CVVHD vs CVVH or CVVHDF

It is very uncertain whether CVVHD changes recovery of kidney function compared with CVVH or CVVHDF (very low certainty).

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  RR 0.91 [0.37, 2.21]
  2 studies · 93 participants
  Very low

Flat plate vs hollow fibre filter of the same membrane type

The review found no eligible studies for this question.

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Flat plate vs hollow fibre filter of the same membrane type

The review found no eligible studies for this question.

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Flat plate vs hollow fibre filter of the same membrane type

The review found no eligible studies for this question.

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

More and shorter vs hollow fibre filter of the same membrane type

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 6 participants
  Low

More and shorter vs hollow fibre filter of the same membrane type

The review found no eligible studies for this question.

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

More and shorter vs hollow fibre filter of the same membrane type

The review found no eligible studies for this question.

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

More and shorter vs hollow fibre filter of the same membrane type

The review found no eligible studies for this question.

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

CVVHD vs CVVH or CVVHDF

The review found no eligible studies for this question.

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

CVVHDF vs standard CVVH

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 62 participants
  Low

CVVHDF vs standard CVVH

It is very uncertain whether CVVHDF changes death from any cause at day 28 of compared with CVVH (very low certainty).

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  RR 0.68 [0.52, 0.9]
  1 study · 206 participants
  Very low

CVVHDF vs standard CVVH

It is very uncertain whether CVVHDF changes recovery of kidney function compared with CVVH (very low certainty).

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  RR 1.1 [0.86, 1.41]
  1 study · 96 participants
  Very low

CVVHDF vs standard CVVH

The review found no eligible studies for this question.

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Pre‐dilution vs post‐dilution (as defined by study investigators)

• Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 47 participants
  Low