Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

900 questions · 932 findings · 149 reviews

No studies found 215 · 23.1%GRADE not reported 65 · 7%Very low 234 · 25.1%Low 256 · 27.5%Moderate 134 · 14.4%High 28 · 3%

Prophylactic CPAP vs mechanical ventilation

Combined outcome of death and bronchopulmonary dysplasia defined as death at any time and oxygen dependency at 36 weeks' postmenstrual age · preterm infants

Prophylactic CPAP probably leads to lower combined outcome of death and bronchopulmonary dysplasia defined as… compared with mechanical ventilation (moderate certainty).

1 finding from 1 review

Prophylactic CPAP vs mechanical ventilation

Failed treatment defined as the need for mechanical ventilation · preterm infants

Prophylactic CPAP probably leads to lower failed treatment defined as the need for mechanical ventilation compared with mechanical ventilation (moderate certainty).

1 finding from 1 review

Prophylactic or very early CPAP vs supportive care

Bronchopulmonary dysplasia at 36 weeks defined as oxygen dependency at 36 weeks postmenstrual age · preterm infants

Prophylactic or very early CPAP showed no clear difference in bronchopulmonary dysplasia at 36 weeks defined as oxygen dependency… compared with supportive care (moderate certainty).

1 finding from 1 review

Prophylactic or very early CPAP vs supportive care

Death or oxygen requirement at 36 weeks' postmenstrual age · preterm infants

Prophylactic or very early CPAP showed no clear difference in combined outcome of death and bronchopulmonary dysplasia defined as… compared with supportive care (low certainty).

1 finding from 1 review

Prophylactic CPAP vs mechanical ventilation

Bronchopulmonary dysplasia at 36 weeks defined as oxygen dependency at 36 weeks postmenstrual age · preterm infants

Prophylactic CPAP probably leads to lower bronchopulmonary dysplasia at 36 weeks defined as oxygen dependency… compared with mechanical ventilation (moderate certainty).

1 finding from 1 review