Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,270 questions · 1,480 findings · 174 reviews

No studies found 252 · 17%GRADE not reported 405 · 27.4%Very low 301 · 20.3%Low 284 · 19.2%Moderate 174 · 11.8%High 64 · 4.3%

Betamethasone vs usual care

Transient tachypnoea of the neonate (TTN) · women undergoing planned elective caesarean section at 37 weeks' gestation and beyond for singleton pregnancy

Effect of antenatal corticosteroids (betamethasone) showed no clear difference in transient tachypnoea of the neonate (TTN) compared with usual care prior to planned caesarean at term on maternal and… (low certainty).

1 finding from 1 review

Betamethasone vs usual care

Admission to neonatal special care (all levels) for respiratory morbidity · women undergoing planned elective caesarean section at 37 weeks' gestation and beyond for singleton pregnancy

Effect of antenatal corticosteroids (betamethasone) probably leads to lower admission to neonatal special care (all levels) for respiratory… compared with usual care prior to planned caesarean at term on maternal and… (moderate certainty).

1 finding from 1 review

Betamethasone vs usual care

Need for mechanical ventilation · women undergoing planned elective caesarean section at 37 weeks' gestation and beyond for singleton pregnancy

It is very uncertain whether effect of antenatal corticosteroids (betamethasone) changes need for mechanical ventilation compared with usual care prior to planned caesarean at term on maternal and… (very low certainty).

1 finding from 1 review

Double primary (canine and first molar) tooth extraction vs Single primary (canine) tooth extraction

Time taken for the canine to erupt into the mouth · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)

The review found no eligible studies for this question.

1 finding from 1 review

Double primary (canine and first molar) tooth extraction vs Single primary (canine) tooth extraction

Overall treatment time wearing orthodontic appliances · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)

The review found no eligible studies for this question.

1 finding from 1 review

Tooth-coloured direct restorative materials (composite, compomer, giomer, RMGIC, HVGIC, open-sandwich) vs No comparator

Retention success rate · Children with primary molars requiring proximal (Class II) restorations

For the Rubber dam isolation: Yes subgroup, the 24-month retention success rate was 0.931 (95% CI 0.834-0.973; ungraded).

28 findings from 1 review
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Tooth-coloured direct restorative materials (composite, compomer, giomer, RMGIC, HVGIC, open-sandwich) vs No comparator

Marginal integrity success rate · Children with primary molars requiring proximal (Class II) restorations

After trim-and-fill adjustment the marginal integrity success rate was 0.881 (95% CI 0.832-0.916; ungraded), a negligible change.

2 findings from 1 review

Tooth-coloured direct restorative materials (composite, compomer, giomer, RMGIC, HVGIC, open-sandwich) vs No comparator

Anatomic form success rate · Children with primary molars requiring proximal (Class II) restorations

The pooled 24-month anatomic form success rate was 0.901 (95% CI 0.845-0.938; ungraded).

2 findings from 1 review

Tooth-coloured direct restorative materials (composite, compomer, giomer, RMGIC, HVGIC, open-sandwich) vs No comparator

Absence of recurrent caries success rate · Children with primary molars requiring proximal (Class II) restorations

After trim-and-fill adjustment the absence-of-recurrent-caries success rate was 0.878 (95% CI 0.828-0.915; ungraded), a negligible change.

2 findings from 1 review

Traditional suburethral sling operation vs a single‐incision sling (mini‐sling)

Number of continent (dry) women (any definition) in the medium term (1 to 5 years) · women with urinary incontinence

It is very uncertain whether traditional suburethral sling operation changes number of continent (dry) women (any definition) in the medium term… compared with a single‐incision sling (mini‐sling) (very low certainty).

1 finding from 1 review

Traditional suburethral sling operation vs a single‐incision sling (mini‐sling)

Perioperative surgical complications ‐ bladder perforation · women with urinary incontinence

It is very uncertain whether traditional suburethral sling operation changes perioperative surgical complications ‐ bladder perforation compared with a single‐incision sling (mini‐sling) (very low certainty).

1 finding from 1 review

Procedures: doffing with double gloves vs doffing with single gloves

Contamination: virus detected ‐ All body parts · healthcare workers

It is very uncertain whether procedures: doffing with double gloves changes contamination: virus detected ‐ all body parts compared with doffing with single gloves (very low certainty).

1 finding from 1 review