Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,171 questions · 1,373 findings · 60 reviews · Dental caries

No studies found 282 · 20.5%GRADE not reported 606 · 44.1%Very low 257 · 18.7%Low 160 · 11.7%Moderate 66 · 4.8%High 2 · 0.1%

ProRoot MTA vs OrthoMTA

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

ProRoot MTA showed no clear difference in clinical failure compared with orthoMTA; GRADE not reported.

1 finding from 1 review

Mineral trioxide aggregate (MTA) vs Buffered glutaraldehyde

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
  • Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
    6 months
    Assessed pain, soft tissue, mobility, radiolucency, root resorption, pulp canal obliteration (Goyal 2016); no clinical/radiological failure outcome; pain, mobility, radiolucency, root resorption significantly favour MTA
    1 study · 60 participants
    GRADE not reported

Mineral trioxide aggregate (MTA) vs Diode laser

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
  • Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
    6 months
    Assessed pain, soft tissue, mobility, radiolucency, root resorption, premature tooth loss (Niranjani 2015); no clinical/radiological failure outcome; no significant differences (RR 0.33, 0.01 to 7.72)
    1 study · 40 participants
    GRADE not reported

3Mix (ciprofloxacin + metronidazole + minocycline) pulpotomy vs 3Mix pulpectomy

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

3Mix (ciprofloxacin + metronidazole + minocycline) pulpotomy showed no clear difference in clinical failure compared with 3Mix pulpectomy; GRADE not reported.

1 finding from 1 review

Calcium-enriched mixture (CEM) cement vs Mineral trioxide aggregate (MTA)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
2 findings from 1 review

ProRoot MTA vs RetroMTA

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

ProRoot MTA showed no clear difference in radiological failure compared with retroMTA; GRADE not reported.

1 finding from 1 review

3Mix (ciprofloxacin + metronidazole + minocycline) pulpotomy vs 3Mix pulpectomy

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

3Mix (ciprofloxacin + metronidazole + minocycline) pulpotomy showed no clear difference in radiological failure compared with 3Mix pulpectomy; GRADE not reported.

1 finding from 1 review