Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

970 questions · 979 findings · 135 reviews

No studies found 182 · 18.6%GRADE not reported 84 · 8.6%Very low 165 · 16.9%Low 311 · 31.8%Moderate 163 · 16.6%High 74 · 7.6%

Vaginal PGE2 pessary vs vaginal PGE2

Caesarean section · women with a previous caesarean section, a live singleton fetus (37‐42 weeks of gestation) in cephalic presentation and a reactive…

It is very uncertain whether vaginal PGE2 pessary changes caesarean section compared with vaginal PGE2 tablet (very low certainty).

1 finding from 1 review

Bishop score vs transvaginal ultrasound

Neonatal admission to NICU · women with singleton cephalic fetuses undergoing assessment for pre‐induction cervical ripening.

Bishop score showed no clear difference in neonatal admission to NICU compared with transvaginal ultrasound (moderate certainty).

1 finding from 1 review

Bishop score vs transvaginal ultrasound

Need of misoprostol for cervical ripening · women with singleton cephalic fetuses undergoing assessment for pre‐induction cervical ripening.

Bishop score probably leads to lower need of misoprostol for cervical ripening compared with transvaginal ultrasound (moderate certainty).

1 finding from 1 review

Bishop score vs transvaginal ultrasound

Meconium staining of amniotic fluid · women with singleton cephalic fetuses undergoing assessment for pre‐induction cervical ripening.

Bishop score showed no clear difference in meconium staining of amniotic fluid compared with transvaginal ultrasound (moderate certainty).

1 finding from 1 review

Bishop score vs transvaginal ultrasound

Apgar score less than 7 at 5 minutes · women with singleton cephalic fetuses undergoing assessment for pre‐induction cervical ripening.

Bishop score showed no clear difference in apgar score at 5 minutes less than 7 compared with transvaginal ultrasound (moderate certainty).

1 finding from 1 review

Magnesium sulphate vs placebo (outcomes

Death or cerebral palsy · women at risk of preterm birth (< 34 weeks' gestation)

Magnesium sulphate showed no clear difference in death or cerebral palsy (up to school age)** compared with placebo (outcomes (low certainty).

2 findings from 1 review

Magnesium sulphate vs placebo (outcomes

Major neurodevelopmental disability at childhood · women at risk of preterm birth (< 34 weeks' gestation)

It is very uncertain whether magnesium sulphate changes major neurodevelopmental disability (school age)** compared with placebo (outcomes (very low certainty).

1 finding from 1 review

Magnesium sulphate vs placebo (outcomes

Death or major neurodevelopmental disability · women at risk of preterm birth (< 34 weeks' gestation)

Magnesium sulphate showed no clear difference in death or major neurodevelopmental disability (up to school age)** compared with placebo (outcomes (low certainty).

2 findings from 1 review

Magnesium sulphate vs placebo (outcomes

Severe maternal outcome potentially related to treatment (death, respiratory arrest, or cardiac arrest)** · women at risk of preterm birth (< 34 weeks' gestation)

Magnesium sulphate showed no clear difference in severe maternal outcome potentially related to treatment (death,… compared with placebo (outcomes (low certainty).

1 finding from 1 review

Magnesium sulphate vs placebo (outcomes

Cerebral palsy · women at risk of preterm birth (< 34 weeks' gestation)

Magnesium sulphate leads to lower cerebral palsy (up to 2 years' corrected age)** compared with placebo (outcomes (high certainty).

2 findings from 1 review

Magnesium sulphate vs placebo (outcomes

Major disability by 18 to 24 months corrected age (aligned definition) · women at risk of preterm birth (< 34 weeks' gestation)

Magnesium sulphate showed no clear difference in major neurodevelopmental disability (up to 2 years' corrected age)** compared with placebo (outcomes (moderate certainty).

1 finding from 1 review