Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

954 questions · 963 findings · 130 reviews · Headline outcomes only

No studies found 181 · 18.8%GRADE not reported 71 · 7.4%Very low 163 · 16.9%Low 311 · 32.3%Moderate 163 · 16.9%High 74 · 7.7%

Double‐balloon catheter vs vaginal PGE2

Caesarean section · women with a previous caesarean section (subgroup of all women in the study) with intact fetal membranes, cephalic position and…

It is very uncertain whether double‐balloon catheter changes caesarean section compared with vaginal PGE2 (very low certainty).

1 finding from 1 review

Vaginal PGE2 pessary vs vaginal PGE2

Caesarean section · women with a previous caesarean section, a live singleton fetus (37‐42 weeks of gestation) in cephalic presentation and a reactive…

It is very uncertain whether vaginal PGE2 pessary changes caesarean section compared with vaginal PGE2 tablet (very low certainty).

1 finding from 1 review

Bishop score vs transvaginal ultrasound

Neonatal admission to NICU · women with singleton cephalic fetuses undergoing assessment for pre‐induction cervical ripening.

Bishop score showed no clear difference in neonatal admission to NICU compared with transvaginal ultrasound (moderate certainty).

1 finding from 1 review

Bishop score vs transvaginal ultrasound

Need of misoprostol for cervical ripening · women with singleton cephalic fetuses undergoing assessment for pre‐induction cervical ripening.

Bishop score probably leads to lower need of misoprostol for cervical ripening compared with transvaginal ultrasound (moderate certainty).

1 finding from 1 review

Bishop score vs transvaginal ultrasound

Meconium staining of amniotic fluid · women with singleton cephalic fetuses undergoing assessment for pre‐induction cervical ripening.

Bishop score showed no clear difference in meconium staining of amniotic fluid compared with transvaginal ultrasound (moderate certainty).

1 finding from 1 review

Bishop score vs transvaginal ultrasound

Apgar score less than 7 at 5 minutes · women with singleton cephalic fetuses undergoing assessment for pre‐induction cervical ripening.

Bishop score showed no clear difference in apgar score at 5 minutes less than 7 compared with transvaginal ultrasound (moderate certainty).

1 finding from 1 review

Magnesium sulphate vs placebo (outcomes

Death or cerebral palsy · women at risk of preterm birth (< 34 weeks' gestation)

Magnesium sulphate showed no clear difference in death or cerebral palsy (up to school age)** compared with placebo (outcomes (low certainty).

2 findings from 1 review

Magnesium sulphate vs placebo (outcomes

Major neurodevelopmental disability at childhood · women at risk of preterm birth (< 34 weeks' gestation)

It is very uncertain whether magnesium sulphate changes major neurodevelopmental disability (school age)** compared with placebo (outcomes (very low certainty).

1 finding from 1 review

Magnesium sulphate vs placebo (outcomes

Death or major neurodevelopmental disability · women at risk of preterm birth (< 34 weeks' gestation)

Magnesium sulphate showed no clear difference in death or major neurodevelopmental disability (up to school age)** compared with placebo (outcomes (low certainty).

2 findings from 1 review

Magnesium sulphate vs placebo (outcomes

Severe maternal outcome potentially related to treatment (death, respiratory arrest, or cardiac arrest)** · women at risk of preterm birth (< 34 weeks' gestation)

Magnesium sulphate showed no clear difference in severe maternal outcome potentially related to treatment (death,… compared with placebo (outcomes (low certainty).

1 finding from 1 review