Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,126 questions · 1,225 findings · 111 reviews

No studies found 235 · 19.2%GRADE not reported 260 · 21.2%Very low 207 · 16.9%Low 271 · 22.1%Moderate 177 · 14.4%High 75 · 6.1%

Non‐vitamin‐K‐antagonist oral anticoagulants vs placebo

Apixaban (all doses combined) vs placebo · adults after AMI without an indication for anticoagulation
3 findings from 1 review

Non‐vitamin‐K‐antagonist oral anticoagulants vs placebo

Rivaroxaban (all doses combined) vs placebo · adults after AMI without an indication for anticoagulation
3 findings from 1 review

Non‐vitamin‐K‐antagonist oral anticoagulants vs placebo

Dabigatran (all doses combined) vs placebo · adults after AMI without an indication for anticoagulation
3 findings from 1 review

Antioxidant multivitamin and mineral supplement vs placebo or no treatment

Progression to late AMD (neovascular AMD, geographic atrophy or both) · people with AMD

Antioxidant multivitamin and mineral supplement probably leads to lower progression to late AMD (neovascular AMD, geographic atrophy, or both) compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Antioxidant multivitamin and mineral supplement vs placebo or no treatment

Progression to neovascular AMD · people with AMD

Antioxidant multivitamin and mineral supplement probably leads to lower progression to neovascular AMD compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Antioxidant multivitamin and mineral supplement vs placebo or no treatment

Progression to geographic atrophy · people with AMD

Antioxidant multivitamin and mineral supplement showed no clear difference in progression to geographic atrophy compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Antioxidant multivitamin and mineral supplement vs placebo or no treatment

Progression to visual loss (loss of 3 or more lines on logMAR chart) · people with AMD

Antioxidant multivitamin and mineral supplement probably leads to lower progression to visual loss (loss of 3 or more lines on logMAR chart) compared with placebo or no treatment (moderate certainty).

1 finding from 1 review