Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

4,678 questions · 4,859 findings · 283 reviews

No studies found 1,225 · 25.2%GRADE not reported 215 · 4.4%Very low 1,241 · 25.5%Low 1,210 · 24.9%Moderate 776 · 16%High 192 · 4%

Lamotrigine vs carbamazepine

Time to treatment failure (any reason related to treatment) All participants Range of · adults and children with focal onset or generalised onset seizures (generalised tonic‐clonic with or without other generalised seizure…

Summary of findings: lamotrigine probably leads to lower time to treatment failure (any reason related to treatment) All… compared with carbamazepine (moderate certainty).

1 finding from 1 review

Lamotrigine vs carbamazepine

Time to treatment failure (any reason related to treatment) Subgroup: focal onset seizures Range of · adults and children with focal onset or generalised onset seizures (generalised tonic‐clonic with or without other generalised seizure…

Summary of findings: lamotrigine probably leads to lower time to treatment failure (any reason related to treatment)… compared with carbamazepine (moderate certainty).

1 finding from 1 review

Lamotrigine vs carbamazepine

Time to treatment failure (any reason related to treatment) Subgroup: generalised onset seizures Range of · adults and children with focal onset or generalised onset seizures (generalised tonic‐clonic with or without other generalised seizure…

Summary of findings: lamotrigine may leads to lower time to treatment failure (any reason related to treatment)… compared with carbamazepine (low certainty).

1 finding from 1 review

Lamotrigine vs carbamazepine

Time to first seizure ‐ all participants Range of · adults and children with focal onset or generalised onset seizures (generalised tonic‐clonic with or without other generalised seizure…

Summary of findings: lamotrigine leads to higher time to first seizure All participants Range of compared with carbamazepine (high certainty).

1 finding from 1 review

Lamotrigine vs carbamazepine

Time to first seizure (post‐randomisation) Subgroup: focal onset seizures Range of · adults and children with focal onset or generalised onset seizures (generalised tonic‐clonic with or without other generalised seizure…

Summary of findings: lamotrigine leads to higher time to first seizure Subgroup: focal onset seizures Range of compared with carbamazepine (high certainty).

1 finding from 1 review

Lamotrigine vs carbamazepine

Time to first seizure ‐ generalised epilepsy Range of · adults and children with focal onset or generalised onset seizures (generalised tonic‐clonic with or without other generalised seizure…

Summary of findings: lamotrigine showed no clear difference in time to first seizure Subgroup: generalised onset seizures Range of compared with carbamazepine (low certainty).

1 finding from 1 review

Lamotrigine vs carbamazepine

Time to 12‐month remission ‐ all participants Range of · adults and children with focal onset or generalised onset seizures (generalised tonic‐clonic with or without other generalised seizure…

Summary of findings: lamotrigine showed no clear difference in time to 12‐month remission All participants Range of compared with carbamazepine (high certainty).

1 finding from 1 review

Summary of findings: NBAS or NBO vs control

Caregiver knowledge (related to infants' physical capacities, including reflexes and senses) Assessed at postintervention, using multiple choice factual questions; higher scores indicate better outcome · caregiver‐infant dyads
1 finding from 1 review