What do systematic reviews say?

Machine-learning algorithms for dental caries detection vs Different machine-learning algorithms for caries prediction

The review reported 88% accuracy for premolar caries in Lee et al. (Ungraded).

• Uses of Different Machine Learning Algorithms for Diagnosis of Dental Caries. 2022 All outcomes

  Korea · Lee et al., 2018; CNN
  Accuracy 88
  1 study · 3000 participants
  GRADE not reported

Povidone iodine 1% vs control

Povidone iodine 1% led to lower presence of dry socket compared with control; GRADE not reported.

• Local interventions for the management of alveolar osteitis (dry socket) 2022 · Cochrane All outcomes

  Follow-up: median 7 days
  RR 0.36 [0.14, 0.98]
  1 study · 189 participants
  GRADE not reported

Recombinant bovine fibroblast growth factor gel vs control

Recombinant bovine fibroblast growth factor gel led to lower presence of dry socket compared with control; GRADE not reported.

• Local interventions for the management of alveolar osteitis (dry socket) 2022 · Cochrane All outcomes

  Follow-up: median 7 days
  RR 0.10 [0.01, 0.76]
  1 study · 160 participants
  GRADE not reported

Machine-learning algorithms for dental caries detection vs Different machine-learning algorithms for caries prediction

The review reported 82% accuracy for combined molar and premolar caries in Lee et al. (Ungraded).

• Uses of Different Machine Learning Algorithms for Diagnosis of Dental Caries. 2022 All outcomes

  Korea · Lee et al., 2018; CNN
  Accuracy 82
  1 study · 3000 participants
  GRADE not reported

Platelet-rich fibrin (PRF) graft vs control

Platelet rich fibrin showed no clear difference in presence of dry socket compared with control; GRADE not reported.

• Local interventions for the management of alveolar osteitis (dry socket) 2022 · Cochrane All outcomes

  Follow-up: median 7 days
  RR 0.44 [0.15, 1.35]
  1 study · 100 participants
  GRADE not reported

Iodine tampon vs Saline irrigation (monoject syringe)

• Local interventions for the management of alveolar osteitis (dry socket) 2022 · Cochrane All outcomes

  Follow-up: median 7 days
  Iodine tampon versus rinsing with saline in a syringe (Tuk 2019): Iodine tampon 0/54 Monoject with saline 0/54; no events (effect not estimable)
  1 study · 108 participants
  GRADE not reported

Socioeconomic status category vs Not applicable (single-group prevalence)

About 36% of children with caries in LMICs were of low SES (pooled prevalence 0.359, 95% CI 0.167 to 0.578; 4 studies; not GRADE-rated).

• Individual, Family, and Socioeconomic Contributors to Dental Caries in Children from Low- and Middle-Income Countries. 2022 All outcomes

  Low- and middle-income countries (Brazil, Nigeria, Cambodia, Tanzania, Mexico, Ethiopia) · Low SES
  Prevalence 0.359 [0.1673, 0.5779]
  4 studies
  GRADE not reported

Machine-learning algorithms for dental caries detection vs Different machine-learning algorithms for caries prediction

The review reported 97.1% accuracy for root caries prediction in Hung et al. (Ungraded).

• Uses of Different Machine Learning Algorithms for Diagnosis of Dental Caries. 2022 All outcomes

  Jordan · Hung et al., 2019; support vector machine
  Accuracy 97.1
  1 study · 5135 participants
  GRADE not reported

Dental caries assessment (WHO/clinical diagnostic criteria; caries = DMFT>0) vs None (descriptive prevalence; random-effects pooled proportion)

About 39% of children in LMICs had dental caries (pooled prevalence 0.387, 95% CI 0.284 to 0.495; 11 studies; very high heterogeneity I2=99%; not GRADE-rated).

• Individual, Family, and Socioeconomic Contributors to Dental Caries in Children from Low- and Middle-Income Countries. 2022 All outcomes

  Low- and middle-income countries (Brazil, Nigeria, Cambodia, Tanzania, Mexico, Ethiopia)
  Prevalence 0.387 [0.284, 0.495]
  11 studies · 11115 participants
  GRADE not reported

Maternal education attainment vs Not applicable (single-group prevalence)

About 10% of children with caries in LMICs had mothers with no formal education (pooled prevalence 0.101, 95% CI 0.033 to 0.201; 3 studies; not GRADE-rated).

• Individual, Family, and Socioeconomic Contributors to Dental Caries in Children from Low- and Middle-Income Countries. 2022 All outcomes

  Low- and middle-income countries (Brazil, Nigeria, Cambodia, Tanzania, Mexico, Ethiopia) · No formal education
  Prevalence 0.1014 [0.0334, 0.2007]
  3 studies · 1499 participants
  GRADE not reported

Maternal education attainment vs Not applicable (single-group prevalence)

About 42% of children with caries in LMICs had mothers with primary education (pooled prevalence 0.425, 95% CI 0.280 to 0.576; 7 studies; not GRADE-rated).

• Individual, Family, and Socioeconomic Contributors to Dental Caries in Children from Low- and Middle-Income Countries. 2022 All outcomes

  Low- and middle-income countries (Brazil, Nigeria, Cambodia, Tanzania, Mexico, Ethiopia) · Primary education
  Prevalence 0.4246 [0.2799, 0.5763]
  7 studies · 3240 participants
  GRADE not reported

Metronidazole gel 25% (local antibiotic) vs Placebo gel

Metronidazole gel (25%, intrasocket) showed no clear difference in presence of dry socket compared with placebo gel; GRADE not reported.

• Local interventions for the management of alveolar osteitis (dry socket) 2022 · Cochrane All outcomes

  Follow-up: median 7 days
  RR 0.53 [0.23, 1.20]
  1 study · 302 participants
  GRADE not reported

Positive pressure therapy vs placebo

Positive pressure therapy showed no clear difference in improvement in vertigo frequency compared with placebo (low certainty).

• Positive pressure therapy for Ménière’s disease 2023 · Cochrane Headline outcomes only
  RR 1.19 [0.82, 1.71]
  1 study · 77 participants
  Low

Positive pressure therapy vs placebo

• Positive pressure therapy for Ménière’s disease 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 68 participants
  Very low

Positive pressure therapy vs placebo

• Positive pressure therapy for Ménière’s disease 2023 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 202 participants
  Very low

Positive pressure therapy vs placebo

The review found no eligible studies for this question.

• Positive pressure therapy for Ménière’s disease 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Any preprocedural mouth rinse vs Placebo, no rinsing or control

The review found no eligible studies for this question.

• Preprocedural mouth rinses for preventing transmission of infectious diseases through aerosols in dental healthcare… 2022 · Cochrane All outcomes
  SoF tables state 'Not reported'; no included study reported adverse events.
  0 studies
  No studies found

Any preprocedural mouth rinse vs Placebo, no rinsing or control

The review found no eligible studies for this question.

• Preprocedural mouth rinses for preventing transmission of infectious diseases through aerosols in dental healthcare… 2022 · Cochrane All outcomes
  Primary outcome. Not measured by any of the 17 included studies (SoF tables state 'Not reported'); remained a total evidence gap from the protocol.
  0 studies
  No studies found

Any preprocedural mouth rinse vs Placebo, no rinsing or control

The review found no eligible studies for this question.

• Preprocedural mouth rinses for preventing transmission of infectious diseases through aerosols in dental healthcare… 2022 · Cochrane All outcomes
  No included study reported change of oral microbiota.
  0 studies
  No studies found

Any preprocedural mouth rinse vs Placebo, no rinsing or control

The review found no eligible studies for this question.

• Preprocedural mouth rinses for preventing transmission of infectious diseases through aerosols in dental healthcare… 2022 · Cochrane All outcomes
  No included study assessed acceptability or feasibility.
  0 studies
  No studies found