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Evidence found and GRADE certainty

628 questions · 651 findings · 39 reviews · Skin

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No studies found 167 · 25.7%GRADE not reported 47 · 7.2%Very low 80 · 12.3%Low 139 · 21.4%Moderate 174 · 26.7%High 44 · 6.8%

Naftifine 1% cream once or twice daily vs placebo cream once or twice daily

Recurrence · patients with tinea cruris and tinea corporis

Naftifine 1% cream once or twice daily showed no clear difference in relapse or recurrence Evidence of clinical or mycological infection… compared with placebo cream once or twice daily (low certainty).

1 finding from 1 review

Terbinafine 1% cream/gel vs Placebo (vehicle cream)

Adverse effects Reported by investigators 'and' or 'or' participants · patients with tinea cruris and tinea corporis

It is very uncertain whether terbinafine 1% cream/gel changes adverse effects Reported by investigators 'and' or 'or' participants compared with placebo cream/gel (very low certainty).

1 finding from 1 review

Azoles vs placebo

Adverse effects Reported by investigators 'and' or 'or' participants · patients with tinea cruris and tinea corporis

It is very uncertain whether azoles changes adverse effects Reported by investigators 'and' or 'or' participants compared with placebo (very low certainty).

1 finding from 1 review

Terbinafine 1% cream/gel vs Placebo (vehicle cream)

Participant‐judged cure Judgement of treatment as 'good' or 'very good' · patients with tinea cruris and tinea corporis

Terbinafine 1% cream/gel may leads to higher participant‐judged cure Judgement of treatment as 'good' or 'very… compared with placebo cream/gel (low certainty).

1 finding from 1 review

Naftifine 1% cream once or twice daily vs placebo cream once or twice daily

Mycological cure · patients with tinea cruris and tinea corporis

Naftifine 1% cream once or twice daily may leads to higher mycological cure Negative KOH microscopy and culture. Treatment… compared with placebo cream once or twice daily (low certainty).

1 finding from 1 review

Naftifine 1% cream once or twice daily vs placebo cream once or twice daily

Clinical cure · patients with tinea cruris and tinea corporis

Naftifine 1% cream once or twice daily may leads to higher clinical cure Resolution of clinical signs and symptoms at least 2… compared with placebo cream once or twice daily (low certainty).

1 finding from 1 review

Naftifine 1% cream once or twice daily vs placebo cream once or twice daily

Adverse effects Reported by investigators 'and' or 'or' participants · patients with tinea cruris and tinea corporis

It is very uncertain whether naftifine 1% cream once or twice daily changes adverse effects Reported by investigators 'and' or 'or' participants compared with placebo cream once or twice daily (very low certainty).

1 finding from 1 review

Chinese herbal medicines vs placebo

Total effectiveness rate (Analysis 1.1) Clinician's rating · atopic eczema

CHM may leads to higher total effectiveness rate (Analysis 1.1) Clinician's rating compared with placebo (low certainty).

1 finding from 1 review