Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

821 questions · 842 findings · 96 reviews

No studies found 275 · 32.7%GRADE not reported 88 · 10.5%Very low 197 · 23.4%Low 187 · 22.2%Moderate 86 · 10.2%High 9 · 1.1%

Swallowed fluticasone vs prednisone

Clinical improvement (dichotomous) · active EoE pediatric patients

It is very uncertain whether swallowed fluticasone changes clinical improvement at 4 weeks (dichotomous) compared with oral prednisone (very low certainty).

1 finding from 1 review

Swallowed fluticasone vs prednisone

Histological improvement at 4 weeks (dichotomous) · active EoE pediatric patients

It is very uncertain whether swallowed fluticasone changes histological improvement at 4 weeks (dichotomous) compared with oral prednisone (very low certainty).

1 finding from 1 review

Swallowed fluticasone vs prednisone

Endoscopic improvement (dichotomous) · active EoE pediatric patients

It is very uncertain whether swallowed fluticasone changes endoscopic improvement at 4 weeks (dichotomous) compared with oral prednisone (very low certainty).

1 finding from 1 review

Swallowed fluticasone vs prednisone

Withdrawals due to adverse events · active EoE pediatric patients

It is very uncertain whether swallowed fluticasone changes withdrawals due to adverse events at 4 weeks compared with oral prednisone (very low certainty).

1 finding from 1 review

Corticosteroids vs placebo

Endoscopic improvement (dichotomous) · active EoE patients

Corticosteroids showed no clear difference in endoscopic improvement (dichotomous) compared with placebo (low certainty).

1 finding from 1 review