Findings

What do systematic reviews say?

43 questions · 58 findings · 7 reviews

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No studies found 6 · 10.3%GRADE not reported 29 · 50%Very low 8 · 13.8%Low 8 · 13.8%Moderate 7 · 12.1%High 0 · 0%

Hypertonic saline 7% vs xylitol

Adverse events: serious adverse events · adults with cystic fibrosis

1 finding from 1 review

Nebulised hypertonic saline for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 89 participants
Very low

V6 chewing gum / mucin chewing gum vs PTC chewing gum (xylitol/sorbitol/mannitol)

Salivary flow rate · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy,…

1 finding from 1 review

Interventions for the management of dry mouth: topical therapies 2011 · Cochrane All outcomes
Olsson 1991 (crossover, high risk of bias, n=14): both gums increased saliva secretion, peaking 17.5 minutes after chewing started; significant treatment-by-period interaction; no per-group data presented.
1 study · 14 participants
GRADE not reported

Fluoride supplementation (tablets, drops, lozenges or chewing gum) vs Other preventive measures (xylitol lozenges)

Caries increment on permanent tooth surfaces (DMFS, approximal surfaces) · Children and adolescents aged 16 years or less

1 finding from 1 review

Fluoride supplements (tablets, drops, lozenges or chewing gums) for preventing dental caries in children 2011 · Cochrane All outcomes
24-36 months
PF 0.00 [-0.59, 0.59]
1 study · 115 participants
Low