Oxytocin augmentation · women in the third trimester for induction of labour.
It is very uncertain whether oral misoprostol changes oxytocin augmentation compared with vaginal dinoprostone (very low certainty).
1 finding from 1 review
Uterine hyperstimulation without fetal heart rate changes · women in the third trimester for induction of labour.
Oral misoprostol probably leads to lower uterine hyperstimulation without fetal heart rate changes compared with vaginal dinoprostone (moderate certainty).
1 finding from 1 review
Apgar score less than 7 at 5 minutes · women in the third trimester for induction of labour.
Oral misoprostol showed no clear difference in apgar score less than seven at five minutes compared with vaginal dinoprostone (low certainty).
1 finding from 1 review
Admission to neonatal intensive care unit · women in the third trimester for induction of labour.
Oral misoprostol showed no clear difference in admission to neonatal intensive care unit compared with vaginal dinoprostone (low certainty).
1 finding from 1 review
Caesarean section · women in the third trimester for induction of labour.
Oral misoprostol probably leads to lower caesarean section compared with vaginal dinoprostone (moderate certainty).
1 finding from 1 review
Mortality due to bleeding · women diagnosed with primary PPH following vaginal birth. Women were suspected to have PPH due to clinical atony and who were quote:…
It is very uncertain whether intrauterine balloon tamponade plus normal care (misoprostol) changes mortality due to bleeding compared with normal care (misoprostol) (very low certainty).
1 finding from 1 review
Hysterectomy to control bleeding · women diagnosed with primary PPH following vaginal birth. Women were suspected to have PPH due to clinical atony and who were quote:…
It is very uncertain whether intrauterine balloon tamponade plus normal care (misoprostol) changes hysterectomy to control bleeding compared with normal care (misoprostol) (very low certainty).
1 finding from 1 review
Serious maternal morbidity (renal or respiratory failure, cardiac arrest or multiple organ failure) · women diagnosed with primary PPH following vaginal birth. Women were suspected to have PPH due to clinical atony and who were quote:…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Number of women with total blood loss 1000 mL or more after randomisation · women diagnosed with primary PPH following vaginal birth. Women were suspected to have PPH due to clinical atony and who were quote:…
It is very uncertain whether intrauterine balloon tamponade plus normal care (misoprostol) changes number of women with total blood loss 1000 mL or more after… compared with normal care (misoprostol) (very low certainty).
1 finding from 1 review
Mean blood loss (mL) (trialist defined) · women diagnosed with primary PPH following vaginal birth. Women were suspected to have PPH due to clinical atony and who were quote:…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Blood transfusion (red cell or whole blood) · women diagnosed with primary PPH following vaginal birth. Women were suspected to have PPH due to clinical atony and who were quote:…
It is very uncertain whether intrauterine balloon tamponade plus normal care (misoprostol) changes blood transfusion (red cell or whole blood) compared with normal care (misoprostol) (very low certainty).
1 finding from 1 review
Side effects of the intervention (e.g. trauma, necrosis) ‐ Severe shivering, diarrhoea, vomiting or high temperature · women diagnosed with primary PPH following vaginal birth. Women were suspected to have PPH due to clinical atony and who were quote:…
1 finding from 1 review
Vaginal delivery not achieved within 24 hours · third trimester induction of labour in women with a viable fetus
Balloon (Foley or ATAD) showed no clear difference in vaginal delivery not achieved in 24 hours compared with low‐dose vaginal misoprostol (low certainty).
1 finding from 1 review
Spontaneous vaginal birth ‐ not reported · pregnant women carrying a live fetus at or near term (≥ 36 weeks' gestation).
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Vaginal delivery not achieved within 24 hours · third trimester induction of labour in women with a viable fetus
Balloon (Foley or ATAD) probably leads to higher vaginal delivery not achieved within 24 hours compared with low‐dose oral misoprostol (moderate certainty).
1 finding from 1 review
Need of misoprostol for cervical ripening · women with singleton cephalic fetuses undergoing assessment for pre‐induction cervical ripening.
Bishop score probably leads to lower need of misoprostol for cervical ripening compared with transvaginal ultrasound (moderate certainty).
1 finding from 1 review
Caesarean section · third trimester induction of labour in women with a viable fetus
Balloon (Foley or ATAD) may leads to higher caesarean section compared with low‐dose vaginal misoprostol (low certainty).
1 finding from 1 review
Serious neonatal morbidity or perinatal death · third trimester induction of labour in women with a viable fetus
It is very uncertain whether balloon (Foley or ATAD) changes serious neonatal morbidity or perinatal death compared with low‐dose vaginal misoprostol (very low certainty).
1 finding from 1 review
Serious maternal morbidity or death · third trimester induction of labour in women with a viable fetus
1 finding from 1 review
Apgar score less than 7 at 5 minutes · third trimester induction of labour in women with a viable fetus
Balloon (Foley or ATAD) showed no clear difference in apgar score < 7 at 5 minutes compared with low‐dose vaginal misoprostol (low certainty).
1 finding from 1 review