Findings

What do systematic reviews say?

49 questions · 49 findings · 7 reviews

No studies found 14 · 28.6%GRADE not reported 0 · 0%Very low 24 · 49%Low 9 · 18.4%Moderate 2 · 4.1%High 0 · 0%

All‐cause mortality · patients with primary biliary cirrhosis.

It is very uncertain whether bezafibrate changes all‐cause mortality compared with ursodeoxycholic acid (very low certainty).

1 finding from 1 review

Bezafibrate for primary biliary cirrhosis 2012 · Cochrane Headline outcomes only
RD 0
2 studies · 69 participants
Very low

Liver morbidity · patients with primary biliary cirrhosis.

It is very uncertain whether bezafibrate changes liver morbidity compared with ursodeoxycholic acid (very low certainty).

1 finding from 1 review

Bezafibrate for primary biliary cirrhosis 2012 · Cochrane Headline outcomes only
RD 0
2 studies · 69 participants
Very low

Change of hepatocellular enzymes1 · adults and children with cystic fibrosis‐related liver disease

1 finding from 1 review

Ursodeoxycholic acid for cystic fibrosis‐related liver disease 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 16 participants
Very low

Abnormally large livers reduced to within normal limits, as measured by ultrasound · adults and children with cystic fibrosis‐related liver disease

The review found no eligible studies for this question.

1 finding from 1 review

Ursodeoxycholic acid for cystic fibrosis‐related liver disease 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Need for liver transplantation · adults and children with cystic fibrosis‐related liver disease

1 finding from 1 review

Ursodeoxycholic acid for cystic fibrosis‐related liver disease 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 58 participants
Very low

Mortality · adults and children with cystic fibrosis‐related liver disease

1 finding from 1 review

Ursodeoxycholic acid for cystic fibrosis‐related liver disease 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 58 participants
Low

Nutritional status: change in weight (kg) · adults and children with cystic fibrosis‐related liver disease

1 finding from 1 review

Ursodeoxycholic acid for cystic fibrosis‐related liver disease 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 30 participants
Low

Development of portal hypertension · adults and children with cystic fibrosis‐related liver disease

1 finding from 1 review

Ursodeoxycholic acid for cystic fibrosis‐related liver disease 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 30 participants
Low

Improved abnormal biliary excretion · adults and children with cystic fibrosis‐related liver disease

1 finding from 1 review

Ursodeoxycholic acid for cystic fibrosis‐related liver disease 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 12 participants
Low