Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

88 questions · 89 findings · 3 reviews · Implants and prosthodontics

No studies found 17 · 19.1%GRADE not reported 47 · 52.8%Very low 22 · 24.7%Low 3 · 3.4%Moderate 0 · 0%High 0 · 0%

Autogenous bone graft augmentation at the immediate implant site vs No augmentation

Prosthesis failure · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)

Autogenous bone graft augmentation at the immediate implant site led to lower prosthesis failure compared with no augmentation; GRADE not reported.

1 finding from 1 review

Resorbable barrier (guided bone regeneration) vs Non-resorbable barrier (guided bone regeneration)

Bone gain (horizontal - HDD) · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)

Resorbable barrier (guided bone regeneration) showed no clear difference in bone gain (horizontal - HDD) compared with non-resorbable barrier (guided bone regeneration); GRADE not reported.

1 finding from 1 review

Bio-Oss (anorganic bovine bone) vs Bovine-derived xenograft (Bio-Oss) plus resorbable barrier

Vertical bone gain · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)

Bio-Oss (anorganic bovine bone) showed no clear difference in bone gain (vertical - VDH) compared with bio-Oss + resorbable barrier; GRADE not reported.

1 finding from 1 review

Non-resorbable barrier (guided bone regeneration) vs Resorbable barrier + particulate autogenous bone

Major complications at the implant/donor site · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)

Non-resorbable barrier (guided bone regeneration) led to lower major complications at the implant/donor site compared with resorbable barrier + autogenous bone; GRADE not reported.

1 finding from 1 review

Resorbable barrier (guided bone regeneration) vs Non-resorbable barrier (guided bone regeneration)

Vertical bone gain · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)

Resorbable barrier (guided bone regeneration) showed no clear difference in bone gain (vertical - VDH) compared with non-resorbable barrier (guided bone regeneration); GRADE not reported.

1 finding from 1 review

Resorbable barrier (guided bone regeneration) vs Resorbable barrier + particulate autogenous bone

Vertical bone gain · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)

Resorbable barrier (guided bone regeneration) showed no clear difference in bone gain (vertical - VDH) compared with resorbable barrier + autogenous bone; GRADE not reported.

1 finding from 1 review

Resorbable barrier (guided bone regeneration) vs Resorbable barrier + particulate autogenous bone

Bone gain (horizontal - HDD) · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)

Resorbable barrier (guided bone regeneration) showed no clear difference in bone gain (horizontal - HDD) compared with resorbable barrier + autogenous bone; GRADE not reported.

1 finding from 1 review

Resorbable barrier (guided bone regeneration) vs Resorbable barrier + particulate autogenous bone

Major complications at the implant/donor site · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)

Resorbable barrier (guided bone regeneration) led to lower major complications at the implant/donor site compared with resorbable barrier + autogenous bone; GRADE not reported.

1 finding from 1 review

Bio-Oss (anorganic bovine bone) vs Bovine-derived xenograft (Bio-Oss) plus resorbable barrier

Major complication at augmented site · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)

Bio-Oss (anorganic bovine bone) led to lower major complications at the augmented site compared with bio-Oss + resorbable barrier; GRADE not reported.

1 finding from 1 review

Autogenous bone graft augmentation at the immediate implant site vs No augmentation

Implant failure · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)

Autogenous bone graft augmentation at the immediate implant site led to lower implant failure compared with no augmentation; GRADE not reported.

1 finding from 1 review

Bio-Oss (anorganic bovine bone) vs Bovine-derived xenograft (Bio-Oss) plus resorbable barrier

Aesthetics · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)

Bio-Oss (anorganic bovine bone) led to lower poor aesthetics measured by dentist (after restoration) compared with bio-Oss + resorbable barrier; GRADE not reported.

1 finding from 1 review

Resorbable barrier (guided bone regeneration) vs Non-resorbable barrier (guided bone regeneration)

Major complications at the implant/donor site · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)

Resorbable barrier (guided bone regeneration) led to lower major complications at the implant/donor site compared with non-resorbable barrier (guided bone regeneration); GRADE not reported.

1 finding from 1 review

Autogenous bone graft augmentation at the immediate implant site vs No augmentation

Major complications at the implant/donor site · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)

Autogenous bone graft augmentation at the immediate implant site led to lower major complications at the implant/donor site compared with no augmentation; GRADE not reported.

1 finding from 1 review

Autogenous bone graft augmentation at the immediate implant site vs No augmentation

Vertical bone gain · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)

Autogenous bone graft augmentation at the immediate implant site showed no clear difference in bone gain (vertical - VDH) compared with no augmentation; GRADE not reported.

1 finding from 1 review

Bio-Oss (anorganic bovine bone) vs Bovine-derived xenograft (Bio-Oss) plus resorbable barrier

Poor aesthetics measured by patient (after restoration) · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)

Bio-Oss (anorganic bovine bone) led to lower poor aesthetics measured by patient (after restoration) compared with bio-Oss + resorbable barrier; GRADE not reported.

1 finding from 1 review

Autogenous bone graft augmentation at the immediate implant site vs No augmentation

Bone gain (horizontal - HDD) · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)

Autogenous bone graft augmentation at the immediate implant site showed no clear difference in bone gain (horizontal - HDD) compared with no augmentation; GRADE not reported.

1 finding from 1 review

Bio-Oss (anorganic bovine bone) vs Bovine-derived xenograft (Bio-Oss) plus resorbable barrier

Augmentation (prosthesis/implant) failure · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)

Bio-Oss (anorganic bovine bone) led to lower augmentation (prosthesis/implant) failure compared with bio-Oss + resorbable barrier; GRADE not reported.

1 finding from 1 review

Bio-Oss (anorganic bovine bone) vs Bovine-derived xenograft (Bio-Oss) plus resorbable barrier

Poor aesthetics measured by dentist (3 years) · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)

Bio-Oss (anorganic bovine bone) led to lower poor aesthetics measured by dentist (3 years) compared with bio-Oss + resorbable barrier; GRADE not reported.

1 finding from 1 review

ARP with demineralised bone matrix, single particle size vs ARP with demineralised bone matrix, multiple particle size

Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
1 finding from 1 review

ARP with alloplast plus barrier membrane vs ARP with alloplast without membrane

Changes in vertical height of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with alloplast plus barrier membrane changes changes in vertical height of alveolar ridge (mm) compared with ARP with alloplast without membrane (very low certainty).

1 finding from 1 review