Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

46 questions · 46 findings · 2 reviews · Skin

No studies found 0 · 0%GRADE not reported 11 · 23.9%Very low 17 · 37%Low 15 · 32.6%Moderate 3 · 6.5%High 0 · 0%

Terbinafine 1% cream/gel vs Placebo (vehicle cream)

Participant‐judged cure Judgement of treatment as 'good' or 'very good' · patients with tinea cruris and tinea corporis

Terbinafine 1% cream/gel may leads to higher participant‐judged cure Judgement of treatment as 'good' or 'very… compared with placebo cream/gel (low certainty).

1 finding from 1 review

Naftifine 1% cream once or twice daily vs placebo cream once or twice daily

Mycological cure · patients with tinea cruris and tinea corporis

Naftifine 1% cream once or twice daily may leads to higher mycological cure Negative KOH microscopy and culture. Treatment… compared with placebo cream once or twice daily (low certainty).

1 finding from 1 review

Naftifine 1% cream once or twice daily vs placebo cream once or twice daily

Clinical cure · patients with tinea cruris and tinea corporis

Naftifine 1% cream once or twice daily may leads to higher clinical cure Resolution of clinical signs and symptoms at least 2… compared with placebo cream once or twice daily (low certainty).

1 finding from 1 review

Naftifine 1% cream once or twice daily vs placebo cream once or twice daily

Adverse effects Reported by investigators 'and' or 'or' participants · patients with tinea cruris and tinea corporis

It is very uncertain whether naftifine 1% cream once or twice daily changes adverse effects Reported by investigators 'and' or 'or' participants compared with placebo cream once or twice daily (very low certainty).

1 finding from 1 review