Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

99 questions · 112 findings · 20 reviews

No studies found 7 · 6.3%GRADE not reported 1 · 0.9%Very low 27 · 24.1%Low 59 · 52.7%Moderate 17 · 15.2%High 1 · 0.9%

Transference‐Focused Psychotherapy (TFP) vs community treatment by experts (CTBE)

Suicidality ‐ CBT vs. TAUno. of participants with suicidal act (last 12 months) · patients with borderline personality disorder

Transference‐Focused Psychotherapy (TFP) showed no clear difference in suicidalityno. of participants with suicidal act (last 12 months) compared with community treatment by experts (CTBE) (moderate certainty).

1 finding from 1 review

Transference‐Focused Psychotherapy (TFP) vs community treatment by experts (CTBE)

Parasuicidality ‐ CBT vs. TAUno. of participants with self‐harming behaviour (last 12 months) · patients with borderline personality disorder

Transference‐Focused Psychotherapy (TFP) showed no clear difference in parasuicidalityno. of participants with self‐harming behaviour (last… compared with community treatment by experts (CTBE) (moderate certainty).

1 finding from 1 review

Psychotherapy as an adjunct to usual care vs usual care

Depressive symptoms · treatment‐resistant depression in adults

Psychotherapy as an adjunct to usual care showed no clear difference in self‐reported depressive symptoms short term (up to 6 months) ‐ BDI… compared with usual care alone (moderate certainty).

8 findings from 1 review
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Psychotherapy as an adjunct to usual care vs usual care

Dropout · treatment‐resistant depression in adults

Psychotherapy as an adjunct to usual care showed no clear difference in dropout medium term (7 to 12 months)* compared with usual care alone (moderate certainty).

2 findings from 1 review

Psychotherapy as an adjunct to usual care vs usual care

Response (50% reduction in BDI) medium term (7 to 12 months)* · treatment‐resistant depression in adults

Psychotherapy as an adjunct to usual care may leads to higher response (50% reduction in BDI) medium term (7 to 12 months)* compared with usual care alone (low certainty).

1 finding from 1 review

Psychotherapy as an adjunct to usual care vs usual care

Response (50% reduction in BDI) long term (longer than 12 months)* · treatment‐resistant depression in adults

Psychotherapy as an adjunct to usual care may leads to higher response (50% reduction in BDI) long term (longer than 12 months)* compared with usual care alone (low certainty).

1 finding from 1 review

Psychotherapy as an adjunct to usual care vs usual care

Remission · treatment‐resistant depression in adults

Psychotherapy as an adjunct to usual care probably leads to higher remission (< 7 on HAMD or < 10 on BDI) medium term (7 to 12 months)* compared with usual care alone (moderate certainty).

2 findings from 1 review

Psychotherapy as an adjunct to usual care vs usual care

> 50% reduction in depressive symptoms · treatment‐resistant depression in adults

Psychotherapy as an adjunct to usual care may leads to higher response (50% reduction in depressive symptoms from baseline) short… compared with usual care alone (low certainty).

1 finding from 1 review

Dynamic‐Deconstructive Psychotherapy (DDP) vs treatment

Parasuicidalityno. of participants with parasuicide (last 3 months) · patients with borderline personality disorder

Dynamic‐Deconstructive Psychotherapy (DDP) showed no clear difference in parasuicidalityno. of participants with parasuicide (last 3 months) compared with treatment (low certainty).

1 finding from 1 review

Comparison 1: Individual CBT‐based psychotherapy vs TAU or another comparator

Repetition of SH at post‐intervention · self‐harm in children and adolescents (up to 18 years or age)

Comparison 1: Individual CBT‐based psychotherapy showed no clear difference in repetition of SH by post‐intervention compared with TAU or other comparator (low certainty).

1 finding from 1 review