Findings

What do systematic reviews say?

42 questions · 47 findings · 2 reviews · Oral medicine and oral cancer

No studies found 5 · 10.6%GRADE not reported 27 · 57.4%Very low 7 · 14.9%Low 8 · 17%Moderate 0 · 0%High 0 · 0%

Salivary flow rate (unstimulated) · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region

1 finding from 1 review

Pharmacological interventions for preventing dry mouth and salivary gland dysfunction following radiotherapy 2017 · Cochrane All outcomes
End of RT
Insufficient evidence, from a single trial of 60 participants, to determine the effect on unstimulated salivary flow rate at the end of RT (Rode 1999; Analysis 2.1)
1 study · 60 participants
GRADE not reported

Dry mouth (xerostomia) · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for preventing dry mouth and salivary gland dysfunction following radiotherapy 2017 · Cochrane All outcomes
No xerostomia data related to the effectiveness of biperiden and pilocarpine were reported (Rode 1999).
0 studies
No studies found