Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

69 questions · 69 findings · 5 reviews · Headline outcomes only

No studies found 28 · 40.6%GRADE not reported 1 · 1.4%Very low 15 · 21.7%Low 12 · 17.4%Moderate 11 · 15.9%High 2 · 2.9%

Statins vs control

Early all‐cause mortality (≤ 3 months) Reported at: 28 days; 60 days; and during hospital stay · adults with acute respiratory distress syndrome

Statins showed no clear difference in early all‐cause mortality (≤ 3 months) Reported at: 60 days; and… compared with control (moderate certainty).

1 finding from 1 review

Beta‐agonist vs control

Early all‐cause mortality (≤ 3 months) Reported at: 28 days; 60 days; and during hospital stay · adults with acute respiratory distress syndrome

Beta‐agonist showed no clear difference in early all‐cause mortality (≤ 3 months) Reported at: 28 days; 60… compared with control (moderate certainty).

1 finding from 1 review