Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

42 questions · 42 findings · 3 reviews · Headline outcomes only

No studies found 0 · 0%GRADE not reported 1 · 2.4%Very low 2 · 4.8%Low 20 · 47.6%Moderate 10 · 23.8%High 9 · 21.4%

Multiple vs single‐injection technique

Secondary analgesia failure: Intraoperative sedation required · Adult patients undergoing hand, wrist or forearm surgery

Multiple showed no clear difference in secondary analgesia failure ‐ intraoperative sedation required compared with single‐injection technique (high certainty).

1 finding from 1 review