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Evidence found and GRADE certainty

128 questions · 130 findings · 12 reviews · Epilepsy

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No studies found 18 · 13.8%GRADE not reported 5 · 3.8%Very low 3 · 2.3%Low 47 · 36.2%Moderate 37 · 28.5%High 20 · 15.4%

Sulthiame vs levetiracetam

Gastrointestinal adverse events · participants with epilepsy (BECTS)

Sulthiame showed no clear difference in adverse effects (gastrointestinal) compared with levetiracetam (low certainty).

1 finding from 1 review

Sulthiame vs levetiracetam

Adverse effects (bones and muscles) · participants with epilepsy (BECTS)

Sulthiame showed no clear difference in adverse effects (bones and muscles) compared with levetiracetam (low certainty).

1 finding from 1 review

Sulthiame vs levetiracetam

Adverse effects (others) · participants with epilepsy (BECTS)

Sulthiame showed no clear difference in adverse effects (others) compared with levetiracetam (low certainty).

1 finding from 1 review

Sulthiame vs phenytoin

All adverse effects · participants with epilepsy (GTCS)

Sulthiame showed no clear difference in all adverse effects compared with phenytoin (low certainty).

1 finding from 1 review

Sulthiame vs phenytoin

Paraesthesia · participants with epilepsy (GTCS)

Sulthiame showed no clear difference in paraesthesia compared with phenytoin (low certainty).

1 finding from 1 review

Sulthiame vs phenytoin

Dizziness · participants with epilepsy (GTCS)

Sulthiame showed no clear difference in dizziness compared with phenytoin (low certainty).

1 finding from 1 review

Sulthiame vs phenytoin

Headache · participants with epilepsy (GTCS)

Sulthiame showed no clear difference in headache compared with phenytoin (low certainty).

1 finding from 1 review

Sulthiame vs phenytoin

Anorexia · participants with epilepsy (GTCS)

Sulthiame showed no clear difference in anorexia compared with phenytoin (low certainty).

1 finding from 1 review

Sulthiame vs phenytoin

Rash · participants with epilepsy (GTCS)

Sulthiame showed no clear difference in rash compared with phenytoin (low certainty).

1 finding from 1 review

Sulthiame vs phenytoin

Gingival hyperplasia · participants with epilepsy (GTCS)

Sulthiame may leads to lower gingival hyperplasia compared with phenytoin (low certainty).

1 finding from 1 review

Sulthiame vs phenytoin

Other · participants with epilepsy (GTCS)

Sulthiame showed no clear difference in other compared with phenytoin (low certainty).

1 finding from 1 review

Sulthiame vs levetiracetam

Treatment withdrawal · participants with epilepsy (BECTS)

Sulthiame showed no clear difference in treatment withdrawal compared with levetiracetam (low certainty).

1 finding from 1 review

Sulthiame vs levetiracetam

Seizure freedom · participants with epilepsy (BECTS)

Sulthiame showed no clear difference in seizure freedom compared with levetiracetam (low certainty).

1 finding from 1 review

Sulthiame vs levetiracetam

Adverse effects (general symptoms) · participants with epilepsy (BECTS)

Sulthiame showed no clear difference in adverse effects (general symptoms) compared with levetiracetam (low certainty).

1 finding from 1 review

Sulthiame vs levetiracetam

Adverse effects (central nervous system) · participants with epilepsy (BECTS)

Sulthiame showed no clear difference in adverse effects (central nervous system) compared with levetiracetam (low certainty).

1 finding from 1 review

Sulthiame vs levetiracetam

Adverse effects (behaviour) · participants with epilepsy (BECTS)

Sulthiame showed no clear difference in adverse effects (behaviour) compared with levetiracetam (low certainty).

1 finding from 1 review