What do systematic reviews say?

Piroxicam vs placebo

• Pharmacological interventions for pain in patients with temporomandibular disorders 2010 · Cochrane All outcomes

  15 days
  Roldan et al 1990 (piroxicam) reported adverse effects. Per the review's Adverse effects of interventions section: 'All but one study (Lobo et al 2004) reported adverse effects. Most of the reported adverse effects…
  1 study · 41 participants
  GRADE not reported

Oral prazepam (benzodiazepine) vs placebo

• Pharmacological interventions for pain in patients with temporomandibular disorders 2010 · Cochrane All outcomes

  8 days
  Rossi et al 1983 (prazepam) reported adverse effects. Per the review's Adverse effects of interventions section: 'All but one study (Lobo et al 2004) reported adverse effects. Most of the reported adverse effects were…
  1 study · 83 participants
  GRADE not reported

Oral diclofenac sodium (NSAID) vs placebo

Oral diclofenac sodium (NSAID) showed no clear difference in daily pain (not improved) compared with placebo; GRADE not reported.

• Pharmacological interventions for pain in patients with temporomandibular disorders 2010 · Cochrane All outcomes

  2 weeks
  RR 0.71 [0.49, 1.04]
  1 study · 32 participants
  GRADE not reported