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Evidence found and GRADE certainty

214 questions · 217 findings · 40 reviews · Pain, Palliative and Supportive Care

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No studies found 35 · 16.1%GRADE not reported 2 · 0.9%Very low 49 · 22.6%Low 43 · 19.8%Moderate 48 · 22.1%High 40 · 18.4%

Summary of findings: serious adverse events (MEC) when vs treatment with granisetron

Interventions (corticosteroids included in all regimens)a · adult cancer patients at risk for CINV caused by moderately emetogenic chemotherapy

The review found no eligible studies for this question.

1 finding from 1 review

Hydromorphone vs oxycodone

Participant‐reported pain intensity VAS (0‐10, lower score = less pain) · people with moderate to severe cancer pain
1 finding from 1 review

Hydromorphone vs morphine

Nausea · people with moderate to severe cancer pain

It is very uncertain whether hydromorphone changes specific adverse events – nausea compared with morphine (very low certainty).

1 finding from 1 review

Hydromorphone vs morphine

Vomiting · people with moderate to severe cancer pain

It is very uncertain whether hydromorphone changes specific adverse events – vomiting compared with morphine (very low certainty).

1 finding from 1 review

Hydromorphone vs morphine

Dizziness · people with moderate to severe cancer pain

It is very uncertain whether hydromorphone changes specific adverse events – dizziness compared with morphine (very low certainty).

1 finding from 1 review

Hydromorphone vs morphine

Quality of life · people with moderate to severe cancer pain

The review found no eligible studies for this question.

1 finding from 1 review

Hydromorphone vs fentanyl

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · people with moderate to severe cancer pain
1 finding from 1 review

Hydromorphone vs fentanyl

Relief of pain · people with moderate to severe cancer pain

The review found no eligible studies for this question.

1 finding from 1 review