Findings

What do systematic reviews say?

42 questions · 42 findings · 4 reviews · Skin

No studies found 11 · 26.2%GRADE not reported 2 · 4.8%Very low 3 · 7.1%Low 8 · 19%Moderate 14 · 33.3%High 4 · 9.5%

Adverse events · participants with confirmed toenail onychomycosis

Terbinafine showed no clear difference in adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Oral antifungal medication for toenail onychomycosis 2017 · Cochrane Headline outcomes only
RR 1.13 [0.87, 1.47]
4 studies · 399 participants
Moderate

Recurrence · participants with confirmed toenail onychomycosis

Terbinafine may leads to lower recurrence rate compared with placebo (low certainty).

1 finding from 1 review

Oral antifungal medication for toenail onychomycosis 2017 · Cochrane Headline outcomes only
RR 0.05 [0.01, 0.38]
1 study · 35 participants
Low