Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,760 questions · 8,065 findings · 1,036 reviews

No studies found 1,686 · 20.9%GRADE not reported 675 · 8.4%Very low 1,953 · 24.2%Low 2,048 · 25.4%Moderate 1,296 · 16.1%High 407 · 5%

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Low vs high 17ß‐oestradiol dose

Uterine volume (cm³) · young women with Turner syndrome who have completed pubertal induction
2 findings from 1 review

Slow vs fast subcutaneous heparin injection

Bruise incidence ‐ 48 hours after injection · patients treated with subcutaneous heparin injections

Slow may leads to lower bruise incidence ‐ 48 hours after injection compared with fast subcutaneous heparin injection (low certainty).

2 findings from 1 review

Low vs higher dose target of rapamycin inhibitor (TOR‐ I): secondary outcomes

Death (all causes) · primary immunosuppression in kidney transplant recipients

Low showed no clear difference in death (all causes) compared with higher dose target of rapamycin inhibitor (TOR‐I): primary outcomes (moderate certainty).

1 finding from 1 review

Low vs higher dose target of rapamycin inhibitor (TOR‐ I): secondary outcomes

Graft loss including death · primary immunosuppression in kidney transplant recipients

Low showed no clear difference in total graft loss (with death) compared with higher dose target of rapamycin inhibitor (TOR‐I): primary outcomes (moderate certainty).

1 finding from 1 review

Low vs higher dose target of rapamycin inhibitor (TOR‐ I): secondary outcomes

Biopsy‐proven acute rejection · primary immunosuppression in kidney transplant recipients

Low probably leads to higher biopsy‐proven acute rejection compared with higher dose target of rapamycin inhibitor (TOR‐I): primary outcomes (moderate certainty).

1 finding from 1 review

Low vs higher dose target of rapamycin inhibitor (TOR‐ I): secondary outcomes

CMV infection · primary immunosuppression in kidney transplant recipients

Low showed no clear difference in CMV infection compared with higher dose target of rapamycin inhibitor (TOR‐I): primary outcomes (moderate certainty).

1 finding from 1 review

Low vs higher dose target of rapamycin inhibitor (TOR‐ I): secondary outcomes

Malignancy · primary immunosuppression in kidney transplant recipients

Low showed no clear difference in all malignancy compared with higher dose target of rapamycin inhibitor (TOR‐I): primary outcomes (moderate certainty).

1 finding from 1 review

Low vs higher dose target of rapamycin inhibitor (TOR‐ I): secondary outcomes

Number needing to change treatment · primary immunosuppression in kidney transplant recipients

Low showed no clear difference in number needing to change treatment compared with higher dose target of rapamycin inhibitor (TOR‐I): primary outcomes (low certainty).

1 finding from 1 review

Low vs higher dose target of rapamycin inhibitor (TOR‐ I): secondary outcomes

Diabetes · primary immunosuppression in kidney transplant recipients

Low probably leads to lower diabetes compared with higher dose target of rapamycin inhibitor (TOR‐ I): secondary outcomes (moderate certainty).

1 finding from 1 review