Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

359 questions · 373 findings · 16 reviews

No studies found 161 · 43.2%GRADE not reported 38 · 10.2%Very low 61 · 16.4%Low 67 · 18%Moderate 35 · 9.4%High 11 · 2.9%

Hypnosis vs No hypnosis (no hypnotic intervention)

Physiological measures during local anaesthesia (pulse rate and oxygen saturation) · Children aged 4 to 13 years with no previous dental experience undergoing restorative treatment with local anaesthesia (Gokli 1994)
1 finding from 1 review
  • With regard to oxygen saturation and pulse rate, only pulse rate was significantly lower in the hypnosis group (P = 0.005); oxygen saturation did not differ significantly. (Gokli 1994; cross-over, 29 children.)
    1 study · 29 participants
    GRADE not reported

Hypnosis vs No hypnosis (no hypnotic intervention)

Measures of behaviour during local anaesthesia administration (undesirable behaviours: crying, hand movement, physical resistance, leg movement) · Children aged 4 to 13 years with no previous dental experience undergoing restorative treatment with local anaesthesia (Gokli 1994)
1 finding from 1 review
  • Patients who were hypnotised demonstrated fewer undesirable behaviours (crying, hand movement, physical resistance and leg movement) than those who did not undergo hypnosis. Decreased crying with hypnosis was the only…
    1 study · 29 participants
    GRADE not reported

Second‐generation endometrial ablation vs first‐generation endometrial ablation

Proportion given local anaesthesia (%) · heavy menstrual bleeding

It is very uncertain whether overall analyses: second‐generation endometrial ablation changes proportion given local anaesthesia (%) compared with first‐generation endometrial ablation (very low certainty).

1 finding from 1 review

Hypnosis vs Inhalation sedation with nitrous oxide and oxygen

Measures of behaviour / negative responses during local anaesthesia administration · Children aged 10 to 16 years undergoing orthodontic extractions (Braithwaite 2005)
1 finding from 1 review
  • Hypnosis can control some of the patient's negative responses to dental treatment, such as movement and behaviour, during administration of local anaesthesia. (Braithwaite 2005; single-blind cross-over, 10 patients…
    1 study · 10 participants
    GRADE not reported

2% mepivacaine, 1:20,000 levonordefrin vs 2% lidocaine, 1:100,000 epinephrine

Duration of anaesthesia (soft tissue, simulated) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

It is very uncertain whether 2% mepivacaine, 1:20,000 levonordefrin changes duration of anaesthesia (soft tissue, simulated) compared with 2% lidocaine, 1:100,000 epinephrine (very low certainty).

1 finding from 1 review

4% articaine, 1:200,000 epinephrine vs 4% articaine, 1:100,000 epinephrine

Duration of anaesthesia (pulpal, electric pulp tester; healthy pulps) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

It is very uncertain whether 4% articaine, 1:200,000 epinephrine changes duration of anaesthesia (pulpal, electric pulp tester; healthy pulps) compared with 4% articaine, 1:100,000 epinephrine (very low certainty).

1 finding from 1 review

4% prilocaine plain vs 2% lidocaine, 1:100,000 epinephrine

Duration of anaesthesia (soft tissue, simulated) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

It is very uncertain whether 4% prilocaine plain changes duration of anaesthesia (soft tissue, simulated) compared with 2% lidocaine, 1:100,000 epinephrine (very low certainty).

1 finding from 1 review

4% articaine, 1:100,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine

Speed of onset of anaesthesia (soft tissue, simulated) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

It is very uncertain whether 4% articaine, 1:100,000 epinephrine changes speed of onset of anaesthesia (soft tissue, simulated) compared with 2% lidocaine, 1:100,000 epinephrine (very low certainty).

1 finding from 1 review

4% prilocaine, 1:200,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine

Speed of onset of anaesthesia (soft tissue, simulated) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

4% prilocaine, 1:200,000 epinephrine showed no clear difference in speed of onset of anaesthesia (soft tissue, simulated) compared with 2% lidocaine, 1:100,000 epinephrine (low certainty).

1 finding from 1 review

4% articaine, 1:200,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine

Duration of anaesthesia (pulpal, electric pulp tester; healthy pulps) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

It is very uncertain whether 4% articaine, 1:200,000 epinephrine changes duration of anaesthesia (pulpal, electric pulp tester; healthy pulps) compared with 2% lidocaine, 1:100,000 epinephrine (very low certainty).

1 finding from 1 review