Phenobarbital vs levetiracetam
Summary of findings table ‐ Phenobarbital showed no clear difference in mortality before hospital discharge compared with levetiracetam (low certainty).
- RR 1.41 [0.82, 2.43]6 studies · 452 participantsLow
Summary of findings table ‐ Phenobarbital showed no clear difference in mortality before hospital discharge compared with levetiracetam (low certainty).
It is very uncertain whether summary of findings table ‐ Phenobarbital changes requirement of mechanical ventilation compared with levetiracetam (very low certainty).
It is very uncertain whether summary of findings table ‐ Phenobarbital changes proportion of infants who develop sedation or drowsiness compared with levetiracetam (very low certainty).
It is very uncertain whether summary of findings table ‐ Phenobarbital changes proportion of infants who develop epilepsy post discharge compared with levetiracetam (very low certainty).
Summary of findings table ‐ Phenobarbital probably leads to higher proportion of infants who achieve seizure control after the maximal… compared with levetiracetam (moderate certainty).
The review found no eligible studies for this question.
It is very uncertain whether summary of findings table ‐ Phenobarbital changes mortality before hospital discharge compared with levetiracetam (very low certainty).
It is very uncertain whether summary of findings table ‐ Phenobarbital changes requirement of mechanical ventilation compared with levetiracetam (very low certainty).
It is very uncertain whether summary of findings table ‐ Phenobarbital changes proportion of infants who develop sedation or drowsiness compared with levetiracetam (very low certainty).
It is very uncertain whether summary of findings table ‐ Phenobarbital changes proportion of infants who develop epilepsy post‐discharge compared with levetiracetam (very low certainty).
It is very uncertain whether summary of findings table ‐ Phenobarbital changes proportion of infants who achieve seizure control after first… compared with levetiracetam (very low certainty).
It is very uncertain whether summary of findings table ‐ Phenobarbital changes proportion of infants who achieve seizure control after maximal… compared with levetiracetam (very low certainty).
Sulthiame showed no clear difference in adverse effects (cardiac) compared with levetiracetam (low certainty).
Sulthiame showed no clear difference in adverse effects (gastrointestinal) compared with levetiracetam (low certainty).
Sulthiame showed no clear difference in adverse effects (bones and muscles) compared with levetiracetam (low certainty).
Sulthiame showed no clear difference in adverse effects (others) compared with levetiracetam (low certainty).
Sulthiame showed no clear difference in treatment withdrawal compared with levetiracetam (low certainty).
Sulthiame showed no clear difference in seizure freedom compared with levetiracetam (low certainty).
Sulthiame showed no clear difference in adverse effects (general symptoms) compared with levetiracetam (low certainty).
Sulthiame showed no clear difference in adverse effects (central nervous system) compared with levetiracetam (low certainty).