Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

89 questions · 91 findings · 6 reviews · Neuromuscular

No studies found 26 · 28.6%GRADE not reported 8 · 8.8%Very low 23 · 25.3%Low 14 · 15.4%Moderate 17 · 18.7%High 3 · 3.3%

IVIg vs placebo

Proportion of participants with side effects attributable to treatment · people with multifocal motor neuropathy

It is very uncertain whether IVIg changes proportion of participants with side effects attributable to treatment compared with placebo (very low certainty).

1 finding from 1 review

Brain‐derived neurotrophic factor vs placebo

Death or disability after 12 months · patients with Guillain‐Barré syndrome

It is very uncertain whether brain‐derived neurotrophic factor changes death or disability after 12 months compared with placebo (very low certainty).

1 finding from 1 review

Brain‐derived neurotrophic factor vs placebo

Participants with 1 or more serious adverse events · patients with Guillain‐Barré syndrome

It is very uncertain whether brain‐derived neurotrophic factor changes participants with 1 or more serious adverse events compared with placebo (very low certainty).

1 finding from 1 review

Cerebrospinal fluid filtration vs plasma exchange

Improvement in disability grade Defined as achievement of a specified degree of improvement · patients with Guillain‐Barré syndrome

It is very uncertain whether cerebrospinal fluid filtration changes improvement in disability grade Defined as achievement of a… compared with plasma exchange (very low certainty).

1 finding from 1 review

Interferon beta‐1a vs placebo

Improvement in disability grade Defined as achievement of a specified degree of improvement · patients with Guillain‐Barré syndrome

It is very uncertain whether interferon beta‐1a changes improvement in disability grade Defined as achievement of a… compared with placebo (very low certainty).

1 finding from 1 review

Cerebrospinal fluid filtration vs plasma exchange

Participants with 1 or more serious adverse events · patients with Guillain‐Barré syndrome

It is very uncertain whether cerebrospinal fluid filtration changes participants with 1 or more serious adverse events compared with plasma exchange (very low certainty).

1 finding from 1 review

Tripterygium polyglycoside vs corticosteroids

Improvement in disability grade Defined as achievement of a specified degree of improvement · patients with Guillain‐Barré syndrome

It is very uncertain whether tripterygium polyglycoside changes improvement in disability grade Defined as achievement of a… compared with corticosteroids (very low certainty).

1 finding from 1 review