Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

85 questions · 85 findings · 15 reviews · Headline outcomes only

No studies found 18 · 21.2%GRADE not reported 0 · 0%Very low 28 · 32.9%Low 19 · 22.4%Moderate 17 · 20%High 3 · 3.5%

Gabapentin vs placebo

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · patients with pain in Guillain‐Barré syndrome

It is very uncertain whether gabapentin changes pain score (numerical rating scale of 0 to 10: 0 = no pain, 10 =… compared with placebo (very low certainty).

1 finding from 1 review

Gabapentin vs placebo

Sedation score (numerical rating scale of 1 to 6: 0 = anxious, agitated, or restless, 6 = asleep, no response) · patients with pain in Guillain‐Barré syndrome

It is very uncertain whether gabapentin changes sedation score (numerical rating scale of 1 to 6: 0 = anxious,… compared with placebo (very low certainty).

1 finding from 1 review